{"id":"W1563674070","doi":"10.18433/j3gk52","title":"Chondroitin Sulfate Capsule System for Efficient and Secure Gene Delivery","year":2010,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministry of Education, Culture, Sports, Science and Technology","keywords":"Gene delivery; Liposome; Cationic polymerization; Cytotoxicity; Transfection; Cationic liposome; Chondroitin sulfate; Chemistry; Transgene; Biophysics; In vivo; Biochemistry; In vitro; Molecular biology; Biology; Polymer chemistry; Gene; Glycosaminoglycan","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805892,0.0004198992,0.0002470795,0.0002659193,0.0001409179,0.0003820853,0.0003301738,0.0003709449,0.0007553927],"category_scores_gemma":[0.000211365,0.0001051106,0.0002482029,0.0002605655,0.0001941034,0.0004009828,0.0003378892,0.0003661154,0.0003141284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005158851,"about_ca_system_score_gemma":0.0005061532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000997916,"about_ca_topic_score_gemma":0.00103875,"domain_scores_codex":[0.9998322,0.0000221655,0.00002148016,0.00004001851,0.00005884675,0.0000252882],"domain_scores_gemma":[0.9998634,0.00001193608,0.00004726457,0.00001484198,0.0000380684,0.00002451953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000519863,0.00002814796,0.0003040904,0.0002228893,0.00002134339,0.00009290673,0.00002013742,0.0002226061,0.990301,0.0004100457,0.0001196361,0.008205214],"study_design_scores_gemma":[0.00001695872,0.0002911251,0.0008636981,0.00001252075,0.00004350692,0.0004294921,0.00001058932,0.002832775,0.9877868,0.00006313272,0.007639017,0.00001039842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9232789,0.02364263,0.04821252,0.0004333451,0.0001690052,0.000216054,0.0002710237,0.0003557115,0.003420725],"genre_scores_gemma":[0.9751639,0.004574202,0.01618665,0.0001269064,0.00002669582,0.00007748539,0.0003509691,0.00003457122,0.003458524],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.000997916,"threshold_uncertainty_score":0.003742993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02831916105246796,"score_gpt":0.3414529884136684,"score_spread":0.3131338273612005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}