{"id":"W1564841886","doi":"10.1186/1742-4690-1-21","title":"Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae","year":2004,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of Manitoba","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"Saccharomyces cerevisiae; Peptide; Mutant; Cell cycle; Cell cycle checkpoint; Gene; Yeast; Biology; Cell biology; Apoptosis; Mutation; Chemistry; Molecular biology; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008427267,0.0003778102,0.0001562716,0.000218292,0.0001251701,0.0002394258,0.0002438201,0.0001594369,0.0007426505],"category_scores_gemma":[0.0001142297,0.00009148745,0.0002454823,0.0002394899,0.0001131534,0.00009403392,0.0001421373,0.0003454947,0.0004013012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000282287,"about_ca_system_score_gemma":0.0001863435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001571684,"about_ca_topic_score_gemma":0.001236029,"domain_scores_codex":[0.999936,0.000009660441,0.00001008831,0.00001226257,0.00002312959,0.000008814523],"domain_scores_gemma":[0.9998943,0.00002544962,0.00003328788,0.00001327459,0.00001736707,0.00001630409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005356079,0.00002042868,0.0002998167,0.00002658138,0.000005990523,0.00005508997,0.000009700672,0.00009925316,0.9986645,0.00003728421,0.00001355304,0.000714276],"study_design_scores_gemma":[0.00001233641,0.000154145,0.004668329,0.00000776,0.00002854079,0.0003169941,0.00003762748,0.0009200239,0.9921772,0.00002881059,0.001642555,0.000005831347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958913,0.000684574,0.001967457,0.00002662426,0.00000916825,0.00003502313,0.0007356699,0.00004757068,0.0006026567],"genre_scores_gemma":[0.9940304,0.0005784372,0.002782155,0.00002280792,0.000002967249,0.00002559121,0.001733409,0.00004188471,0.0007823792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001571684,"threshold_uncertainty_score":0.003125012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297923535142046,"score_gpt":0.2719204705997308,"score_spread":0.2589412352483104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}