{"id":"W1565323904","doi":"10.1158/1538-7445.sabcs14-s1-04","title":"Abstract S1-04: Exome sequencing of post-menopausal ER+ breast cancer (BC) treated pre-surgically with aromatase inhibitors (AIs) in the POETIC trial (CRUK/07/015)","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Exome sequencing; Medicine; Exome; Internal medicine; Cancer; Breast cancer; Oncology; Bioinformatics; Gene; Phenotype; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005058171,0.0002303714,0.0005604354,0.0002319114,0.0002767736,0.0004277064,0.0002536309,0.0004043826,0.01118351],"category_scores_gemma":[0.0008580908,0.0001296725,0.0002665376,0.0003444839,0.0001423334,0.0001416821,0.0002484726,0.0003077208,0.001425233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002574,"about_ca_system_score_gemma":0.0002580837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006774595,"about_ca_topic_score_gemma":0.001097087,"domain_scores_codex":[0.9997992,0.0000701293,0.00001774484,0.0000498493,0.00003615232,0.00002702761],"domain_scores_gemma":[0.9996063,0.0001295362,0.00006468114,0.00006412389,0.00006179834,0.00007354617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.1832103,0.001862502,0.2368047,0.00212953,0.001245817,0.002751137,0.0008647124,0.003760734,0.3353021,0.0007854233,0.07089749,0.1603854],"study_design_scores_gemma":[0.01046544,0.0103902,0.8886781,0.0001332693,0.0007067272,0.003687091,0.0003653621,0.002208966,0.03272097,0.0007224674,0.04987234,0.00004897651],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9394149,0.000956425,0.0009628886,0.0003164539,0.00004451757,0.0003926136,0.05499261,0.00007028092,0.002849211],"genre_scores_gemma":[0.8508539,0.0004589716,0.002690189,0.0005406244,0.00007711332,0.0008620688,0.1367981,0.0001088585,0.007610184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01118351,"threshold_uncertainty_score":0.03741252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0541938834445379,"score_gpt":0.3560474119185176,"score_spread":0.3018535284739797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}