{"id":"W156584023","doi":"10.1007/978-1-4615-1173-1_1","title":"Tumor Physiology and Resistance to Chemotherapy: Repopulation and Drug Penetration","year":2002,"lang":"en","type":"review","venue":"Cancer treatment and research","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Chemotherapy; Breast cancer; Oncology; Internal medicine; Cancer; Disease; Drug resistance; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006329456,0.001250383,0.002510875,0.001338055,0.0003588028,0.00165376,0.00137514,0.001951382,0.002677296],"category_scores_gemma":[0.0005087068,0.000411257,0.0004155025,0.002129436,0.001031456,0.001786639,0.0005708304,0.002090012,0.002695867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000930512,"about_ca_system_score_gemma":0.000739053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009835904,"about_ca_topic_score_gemma":0.001494115,"domain_scores_codex":[0.9997903,0.00003974801,0.00002450918,0.00004324938,0.00007676747,0.00002545209],"domain_scores_gemma":[0.9997771,0.0001024529,0.00002908574,0.00001252683,0.00005943423,0.00001930154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001869075,0.0001281403,0.0002660063,0.006586712,0.00005380062,0.0004083955,0.0000689392,0.0006535671,0.01168802,0.005841559,0.02381323,0.9503047],"study_design_scores_gemma":[0.00003238848,0.0001584377,0.001075378,0.0008214207,0.00009549256,0.002780855,0.0001008753,0.0002327623,0.005143497,0.003699252,0.9858325,0.00002718731],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000279218,0.9970934,0.0006252021,0.0003651514,0.000344057,0.000005829295,0.00001355323,0.00001390886,0.001259643],"genre_scores_gemma":[0.001581476,0.9958614,0.0003706854,0.0002383035,0.0002429126,0.00001264978,0.00002272628,0.000002880842,0.001666979],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002677296,"threshold_uncertainty_score":0.008956432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09295831668175633,"score_gpt":0.4153198950002288,"score_spread":0.3223615783184725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}