{"id":"W1566021824","doi":"10.4049/jimmunol.178.4.2396","title":"Rapid Clonal Expansion and Prolonged Maintenance of Memory CD8+ T Cells of the Effector (CD44highCD62Llow) and Central (CD44highCD62Lhigh) Phenotype by an Archaeosome Adjuvant Independent of TLR2","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; University of Ottawa","funders":"","keywords":"Biology; Cytotoxic T cell; CD8; Priming (agriculture); Immunology; Effector; Adjuvant; FOXP3; Immune system; Molecular biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002019593,0.0002828564,0.0008525444,0.0002025397,0.0001670211,0.000004271466,0.0007058374,0.0003388933,0.0001084629],"category_scores_gemma":[0.0001488785,0.000159705,0.000180063,0.0001746563,0.00228326,0.0001495018,0.0002312513,0.0007829585,0.000001857336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003746953,"about_ca_system_score_gemma":0.0001576846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000188606,"about_ca_topic_score_gemma":0.00002191142,"domain_scores_codex":[0.9965056,0.001495501,0.001154748,0.0001850319,0.0001434614,0.0005156421],"domain_scores_gemma":[0.996803,0.0009231266,0.001467812,0.000496392,0.0002769125,0.000032719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01493314,0.0003297405,0.00082523,0.00005678039,0.0006641231,0.000004359855,0.004086518,0.000006098348,0.9666681,0.0001237955,0.0001357013,0.01216637],"study_design_scores_gemma":[0.003915705,0.003032769,0.1303042,0.0001779352,0.0001469864,0.0005720537,0.001213968,0.000002336255,0.8591961,0.0001090184,0.001186285,0.0001426323],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9235725,0.07464952,0.0001573579,0.0002316167,0.0009801371,0.0003391857,0.00004056629,0.000006617694,0.00002245895],"genre_scores_gemma":[0.993184,0.006421272,0.00006841076,0.00007247055,0.00002776285,0.000001855711,0.000005529339,0.00002519502,0.0001935308],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.129479,"threshold_uncertainty_score":0.8412765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006154876968305829,"score_gpt":0.2112866257231447,"score_spread":0.2051317487548389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}