{"id":"W1566021824","doi":"10.4049/jimmunol.178.4.2396","title":"Rapid Clonal Expansion and Prolonged Maintenance of Memory CD8+ T Cells of the Effector (CD44highCD62Llow) and Central (CD44highCD62Lhigh) Phenotype by an Archaeosome Adjuvant Independent of TLR2","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; University of Ottawa","funders":"","keywords":"Biology; Cytotoxic T cell; CD8; Priming (agriculture); Immunology; Effector; Adjuvant; FOXP3; Immune system; Molecular biology; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009234836,0.0002309683,0.00015058,0.0001135119,0.00008001251,0.0001647833,0.00008555241,0.0001820497,0.0008964292],"category_scores_gemma":[0.0000701861,0.00009605623,0.0001384871,0.00006172796,0.000100215,0.000120675,0.000184724,0.0004493615,0.0003846515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007275312,"about_ca_system_score_gemma":0.00009016734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009063146,"about_ca_topic_score_gemma":0.0002354611,"domain_scores_codex":[0.999934,0.000007787221,0.000005006993,0.00001441124,0.00001424348,0.000024619],"domain_scores_gemma":[0.9999248,0.0000093551,0.00001897403,0.00001185708,0.00001213776,0.00002287957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000475018,0.00002397914,0.0004145813,0.00001371388,0.000001386045,0.00003321572,0.00001436042,0.00002750814,0.9975744,0.00002139843,0.00002334438,0.001804701],"study_design_scores_gemma":[0.00003913931,0.001775922,0.01858318,0.00001491072,0.00002607753,0.00061755,0.00007216445,0.001070917,0.9743983,0.0000877479,0.003308024,0.000006081097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973758,0.000443625,0.001357136,0.00002759633,0.0000118843,0.00002533707,0.00008954805,0.00005175511,0.0006171592],"genre_scores_gemma":[0.996126,0.0002870226,0.00134266,0.00004319986,0.00001662288,0.00003940879,0.0001719938,0.00001140431,0.001961665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008964292,"threshold_uncertainty_score":0.002998829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006154876968305829,"score_gpt":0.2112866257231447,"score_spread":0.2051317487548389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}