{"id":"W1566178411","doi":"10.1002/3527603433.ch7","title":"Initiation of Protein Synthesis","year":2004,"lang":"en","type":"other","venue":"","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Initiation factor; eIF2; Eukaryotic initiation factor; EIF4G; Eukaryotic Small Ribosomal Subunit; EIF4E; Biology; Eukaryotic translation; EIF4A1; Ternary complex; eIF4A; Eukaryotic Ribosome; Eukaryotic translation initiation factor 4 gamma; Cell biology; Internal ribosome entry site; Ribosomal binding site; Ribosome; Biochemistry; Messenger RNA; Translation (biology); RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005288432,0.001733431,0.001564001,0.001173701,0.001108059,0.003464643,0.001306939,0.001454932,0.033731],"category_scores_gemma":[0.0005813952,0.0005805179,0.001268625,0.001280189,0.0005932531,0.001454672,0.001874416,0.00172523,0.05744827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00179903,"about_ca_system_score_gemma":0.00172632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00122725,"about_ca_topic_score_gemma":0.0009552835,"domain_scores_codex":[0.9991308,0.00009122139,0.00006492904,0.0002678237,0.0003020029,0.0001432259],"domain_scores_gemma":[0.9997733,0.00002131866,0.00003291856,0.00004395783,0.00008187669,0.00004666693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007247971,0.0001836856,0.001211296,0.005422741,0.0002212196,0.0008605294,0.0004301724,0.001076096,0.3610159,0.09755757,0.1040034,0.4272926],"study_design_scores_gemma":[0.00003375861,0.0001834271,0.0009360799,0.0002526558,0.00002630658,0.0002877741,0.00005470332,0.0002797781,0.05916277,0.004238013,0.9345191,0.00002563643],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.03532449,0.271863,0.1248561,0.003909316,0.01827422,0.003028527,0.02982954,0.01236771,0.5005472],"genre_scores_gemma":[0.1897909,0.1229239,0.08875699,0.002888952,0.001840767,0.002333044,0.03921393,0.001452151,0.5507994],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.033731,"threshold_uncertainty_score":0.1128415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009920717206671247,"score_gpt":0.2270577315500975,"score_spread":0.2171370143434262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}