{"id":"W1567111707","doi":"10.4049/jimmunol.174.9.5306","title":"Identification of CD4+ T Cell-Specific Epitopes of Islet-Specific Glucose-6-Phosphatase Catalytic Subunit-Related Protein: A Novel β Cell Autoantigen in Type 1 Diabetes","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; Canadian Institutes of Health Research; Western University","funders":"","keywords":"Epitope; Biology; T cell; CD8; NOD mice; Major histocompatibility complex; MHC class I; MHC class II; Protein subunit; Nod; Antigen; Immunology; Biochemistry; Autoimmunity; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430914,0.0004666946,0.0002269183,0.0002571685,0.0001265523,0.0002535194,0.0001830753,0.0006149195,0.0008003149],"category_scores_gemma":[0.0001143115,0.0001236955,0.000235141,0.0001344414,0.0001366456,0.0002465117,0.0002255871,0.0004415342,0.000392586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001304781,"about_ca_system_score_gemma":0.000114774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000724592,"about_ca_topic_score_gemma":0.00008673364,"domain_scores_codex":[0.9999197,0.00001589085,0.00000758755,0.00001939934,0.00001655722,0.00002082464],"domain_scores_gemma":[0.9999284,0.00001266643,0.00001586377,0.000005599711,0.00001094793,0.00002651439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001966931,0.00004728583,0.0009205569,0.000102695,0.000005965089,0.0001944283,0.00001909579,0.00007315341,0.994766,0.00003490924,0.00003210603,0.003607111],"study_design_scores_gemma":[0.0002402283,0.003987969,0.0443906,0.00005831176,0.0001532421,0.00414166,0.0001392637,0.00270334,0.9393411,0.0004080441,0.004416947,0.000019425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962745,0.001667133,0.001153448,0.00004519405,0.00001423733,0.00002510017,0.00007566227,0.00002260374,0.000722222],"genre_scores_gemma":[0.9933442,0.00185426,0.003415773,0.0001124632,0.00005415923,0.00005462191,0.0003693858,0.00001347672,0.0007816773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008003149,"threshold_uncertainty_score":0.002677321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005867730408468359,"score_gpt":0.2022763987003005,"score_spread":0.1964086682918322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}