{"id":"W1567180129","doi":"10.1002/cncr.20691","title":"Two schedules of second‐line irinotecan for metastatic colon carcinoma","year":2004,"lang":"en","type":"article","venue":"Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"Medicine; Irinotecan; Regimen; Toxicity; Quality of life (healthcare); Colorectal cancer; Schedule; Chemotherapy; Cost effectiveness; Clinical trial; Internal medicine; Surgery; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001032754,0.0006502477,0.001519521,0.0005299445,0.000226095,0.0005499555,0.0008510278,0.0009344087,0.00611758],"category_scores_gemma":[0.001688381,0.0004363556,0.001392422,0.000430145,0.0004389568,0.0008335226,0.0004195639,0.001914188,0.0005581955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007026806,"about_ca_system_score_gemma":0.0006860083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000808906,"about_ca_topic_score_gemma":0.001568178,"domain_scores_codex":[0.9993787,0.0002275607,0.00006705467,0.000128255,0.0001085184,0.00008983558],"domain_scores_gemma":[0.9991035,0.0001946246,0.0002719937,0.0001274156,0.0000372804,0.0002651482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7677367,0.02497992,0.002647451,0.001080364,0.001657719,0.00006933217,0.00007689793,0.003826623,0.008312184,0.0004568018,0.001138854,0.1880171],"study_design_scores_gemma":[0.6500583,0.3248134,0.014881,0.0001136227,0.0007038222,0.0002337235,0.00003469166,0.002723932,0.003226515,0.0004895233,0.002668866,0.00005268917],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918724,0.002935567,0.0009406987,0.0003378145,0.0003519957,0.001700768,0.0003523622,0.0001120169,0.001396447],"genre_scores_gemma":[0.9915064,0.001309618,0.002270454,0.0004606236,0.0002225551,0.002256413,0.0004006821,0.00002144099,0.001551835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00611758,"threshold_uncertainty_score":0.02046537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04646847661258846,"score_gpt":0.3550561163952833,"score_spread":0.3085876397826949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}