{"id":"W1568122112","doi":"10.4049/jimmunol.0902505","title":"The Pleckstrin Homology Domain Adaptor Protein Bam32/DAPP1 Is Required for Germinal Center Progression","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research","keywords":"Germinal center; Signal transducing adaptor protein; Biology; B cell; CD40; Cell biology; Signal transduction; Molecular biology; Immunology; Biochemistry; Antibody; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001203237,0.0004578524,0.0002349379,0.0002442589,0.0002114847,0.0003391414,0.0002532725,0.0003384097,0.001244898],"category_scores_gemma":[0.0001894412,0.0002303966,0.000157222,0.000128887,0.000240241,0.000284992,0.0004290565,0.0005702594,0.0009435712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003397598,"about_ca_system_score_gemma":0.0002711556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003693975,"about_ca_topic_score_gemma":0.0003314618,"domain_scores_codex":[0.9998593,0.00001874245,0.0000145675,0.0000364497,0.00003838531,0.00003254784],"domain_scores_gemma":[0.999652,0.00003593653,0.0001294329,0.00003041912,0.00001947518,0.0001328027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005923877,0.000007656426,0.0001952259,0.00001650942,0.000001286198,0.00008585972,0.000006236883,0.00002425346,0.9990546,0.00003604871,0.00002429064,0.0004888031],"study_design_scores_gemma":[0.00002635406,0.0001480025,0.02990477,0.000009829364,0.0000121583,0.00105664,0.00004359261,0.0009565155,0.9642913,0.00009324498,0.003449837,0.000007833363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951519,0.001474029,0.001920743,0.0000659461,0.00002107024,0.00001753009,0.0003773402,0.0001527726,0.0008185138],"genre_scores_gemma":[0.9958617,0.0004367762,0.001040552,0.00002333179,0.000006604914,0.00002145968,0.0008066955,0.00002996056,0.001772908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001244898,"threshold_uncertainty_score":0.004164636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321934805652315,"score_gpt":0.2560092179113181,"score_spread":0.242789869854795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}