{"id":"W1568494879","doi":"10.1002/9780470513927.ch8","title":"Phospholipase C Isozymes: Structural and Functional Similarities","year":2007,"lang":"en","type":"article","venue":"Novartis Foundation symposium","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Gene isoform; Isozyme; Phospholipase C; Tyrosine phosphorylation; Phosphorylation; Phosphatidylinositol; Biochemistry; Phospholipase; SH2 domain; Gq alpha subunit; Biology; Tyrosine; Cell biology; Chemistry; Enzyme; Signal transduction; Gene; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000256593,0.000123538,0.00008293115,0.00005916156,0.0001831882,0.0000619795,0.00004231957,0.0001032659,0.0002012988],"category_scores_gemma":[0.00003305126,0.0001259644,0.00004135555,0.00008685754,0.00009717211,0.00001552866,0.00004791762,0.0000607192,0.00001617084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001818797,"about_ca_system_score_gemma":0.00004340142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001431771,"about_ca_topic_score_gemma":0.00003204096,"domain_scores_codex":[0.9991531,0.00002042383,0.0002151769,0.000260297,0.000159621,0.0001914149],"domain_scores_gemma":[0.9995583,0.00001139766,0.00007226656,0.0001560606,0.0001186079,0.00008341583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001841835,0.00001673742,0.0051352,0.00001723365,0.00002328847,0.000003541246,0.00009079111,0.00008635659,0.984898,0.004064148,0.0005833296,0.004897237],"study_design_scores_gemma":[0.001267144,0.0001678811,0.04128237,0.00001671346,0.00002430191,0.0001060144,0.0001656197,0.0005105289,0.8593615,0.0009662364,0.09574645,0.0003852818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9568779,0.0003279031,0.04022007,0.0004458568,0.0003150436,0.0001684165,0.000009011708,0.00003294504,0.001602873],"genre_scores_gemma":[0.9967185,0.00002732081,0.001090441,0.0005382111,0.0004182222,0.0000082249,0.0003032194,0.00001508747,0.0008807918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1255365,"threshold_uncertainty_score":0.5136679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350764579136756,"score_gpt":0.2558120957335792,"score_spread":0.2423044499422116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}