{"id":"W1569497166","doi":"10.1002/9780470571224.pse304","title":"Unexpected Benefits of a Formulation: Case Study with Erythropoetin","year":2010,"lang":"en","type":"other","venue":"Pharmaceutical Sciences Encyclopedia","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Erythropoietin; Recombinant DNA; Medicine; Concomitant; Dialysis; Anemia; Chronic renal failure; Glycoprotein; Pharmacology; Internal medicine; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001014062,0.001505718,0.0009376491,0.001592878,0.00296135,0.002276564,0.001199692,0.007173814,0.003861221],"category_scores_gemma":[0.006936937,0.0005804775,0.00199587,0.0010076,0.002398349,0.001600197,0.001445019,0.005007823,0.001302004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002258592,"about_ca_system_score_gemma":0.0008778889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002728856,"about_ca_topic_score_gemma":0.003460561,"domain_scores_codex":[0.9987854,0.0003419735,0.0001086128,0.0001900234,0.000357195,0.000216762],"domain_scores_gemma":[0.9968013,0.001609135,0.0005226247,0.0001924784,0.0001740345,0.0007004659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00007576804,0.0002870645,0.001646581,0.00005828738,0.00001910349,0.9929062,0.0003653255,0.0001709057,0.000482576,0.0006826164,0.0007014014,0.002604206],"study_design_scores_gemma":[0.00002594533,0.0003245925,0.001067297,0.00004060335,0.00002574946,0.9916618,0.0003458474,0.0007352966,0.001025535,0.0004413202,0.004289702,0.00001628285],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8976381,0.01148307,0.01166285,0.02896341,0.001680649,0.0007860839,0.0004213609,0.0003154712,0.04704892],"genre_scores_gemma":[0.9732184,0.003176647,0.00475491,0.005071949,0.0007201437,0.00007318461,0.0001081435,0.0001307451,0.01274592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007173814,"threshold_uncertainty_score":0.01638734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0515299663339278,"score_gpt":0.3692711278659384,"score_spread":0.3177411615320106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}