{"id":"W1569514952","doi":"10.1111/j.1462-5822.2011.01602.x","title":"Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation","year":2011,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Amastigote; Cell biology; Unfolded protein response; Protein kinase A; Phosphorylation; Kinase; Leishmania; Endoplasmic reticulum; Parasite hosting","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007456691,0.0002491356,0.0005799307,0.0003032091,0.00006781973,0.00000764092,0.0003875289,0.0001755783,0.000353449],"category_scores_gemma":[0.0002065697,0.0001853524,0.0001421249,0.000410325,0.000283588,0.00006651117,0.0001818511,0.0002873769,0.0000613259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009437309,"about_ca_system_score_gemma":0.00009148797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004977023,"about_ca_topic_score_gemma":0.0001403234,"domain_scores_codex":[0.9978568,0.0002969768,0.000705477,0.0004696036,0.0002299421,0.0004411968],"domain_scores_gemma":[0.9986047,0.0001288335,0.0002862816,0.0005726515,0.0003254419,0.00008207736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006882316,0.0003819619,0.03891277,0.0001556699,0.000128028,0.00003557272,0.005198325,0.00000313209,0.9527009,0.0001712383,0.0007641843,0.000859978],"study_design_scores_gemma":[0.001345777,0.001074306,0.2894974,0.0001450804,0.00007813451,0.00004173271,0.0006910385,0.0001266654,0.7061601,0.0001227054,0.0005315937,0.0001855157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949903,0.0008386719,0.001648122,0.0004647117,0.0001482107,0.001238677,0.00004969676,0.00002115147,0.0006004058],"genre_scores_gemma":[0.9980711,0.00009038052,0.00117885,0.0001815399,0.00004017118,0.00005493266,0.00006902476,0.00002741975,0.0002865558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2505846,"threshold_uncertainty_score":0.7558453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02852525472932279,"score_gpt":0.2580369073890532,"score_spread":0.2295116526597304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}