{"id":"W1569798729","doi":"10.1002/9783527636730.ch1","title":"Peptides as Leads for Drug Discovery","year":2011,"lang":"en","type":"other","venue":"","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Peptidomimetic; Protease; Herpes simplex virus; Drug discovery; Virology; Human immunodeficiency virus (HIV); Drug; Computational biology; Chemistry; Biology; Pharmacology; Peptide; Virus; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004685607,0.0006782684,0.0004587165,0.000676338,0.0003560486,0.001466916,0.0004522009,0.0005271939,0.0186941],"category_scores_gemma":[0.0003553143,0.0002753985,0.0002990373,0.0006023208,0.0005374582,0.001446771,0.0009346054,0.001511205,0.008967811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004883389,"about_ca_system_score_gemma":0.0004034411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001714105,"about_ca_topic_score_gemma":0.0003323352,"domain_scores_codex":[0.9997451,0.00004988635,0.000010375,0.00003588878,0.0001251746,0.00003366215],"domain_scores_gemma":[0.9999272,0.00002344608,0.000009212264,0.00001130635,0.00001439353,0.0000145272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003311858,0.0002424001,0.0002200225,0.002029811,0.00005138331,0.0004445094,0.0002340332,0.002190914,0.1328769,0.2475066,0.04182127,0.572051],"study_design_scores_gemma":[0.00009557017,0.0004853671,0.0001736245,0.0002251787,0.00003128906,0.0003044225,0.0000491825,0.0009478354,0.08273578,0.03022749,0.8847045,0.00001986188],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.03986267,0.2704625,0.1035061,0.007830139,0.006794983,0.0008081487,0.0021922,0.001850248,0.5666931],"genre_scores_gemma":[0.177182,0.3547667,0.06441356,0.004083571,0.002390583,0.0006887387,0.001920138,0.0004716789,0.394083],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0186941,"threshold_uncertainty_score":0.06253803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03556704098858823,"score_gpt":0.3362622206015951,"score_spread":0.3006951796130068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}