{"id":"W1570117617","doi":"10.1002/9780470015902.a0005642.pub2","title":"Informed Consent and Multiplex Genetic Screening","year":2010,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome Canada; McGill University","funders":"","keywords":"Multiplex; Genetic testing; Informed consent; Psychosocial; Medicine; Engineering ethics; Data science; Psychology; Computer science; Bioinformatics; Alternative medicine; Biology; Psychiatry; Pathology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02618573,0.0003903098,0.0003140701,0.0008145409,0.001462861,0.002872214,0.0008551939,0.004752662,0.01289188],"category_scores_gemma":[0.0556266,0.0001759528,0.0003556084,0.0007704139,0.007093493,0.004833743,0.004688549,0.004104645,0.001723739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001674689,"about_ca_system_score_gemma":0.004212817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049488,"about_ca_topic_score_gemma":0.001244303,"domain_scores_codex":[0.97212,0.02135512,0.001542861,0.0008453457,0.003403303,0.0007333761],"domain_scores_gemma":[0.9578652,0.03305747,0.002088634,0.003439446,0.002488529,0.001060766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005121024,0.00004540118,0.001207476,0.0003212996,0.00000844523,0.001856606,0.003501326,0.0003332527,0.0005013005,0.7959347,0.04097234,0.1552666],"study_design_scores_gemma":[0.00003024693,0.00005184245,0.001300842,0.001846806,0.00001222648,0.008127443,0.002102608,0.0008126463,0.001280064,0.581752,0.4026404,0.00004276556],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0192929,0.02006217,0.1026284,0.2195708,0.003148299,0.001030014,0.0003717655,0.0002059728,0.6336898],"genre_scores_gemma":[0.6168533,0.02219368,0.1047252,0.1087772,0.003255328,0.002866606,0.0005782726,0.0001344946,0.140616],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.02618573,"threshold_uncertainty_score":0.138485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02046183313209358,"score_gpt":0.2952918392126884,"score_spread":0.2748300060805948,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}