{"id":"W1570173806","doi":"10.1186/ar1756","title":"Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis","year":2005,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"Murdoch University; Australian Orthopaedic Association","keywords":"Lumican; Biglycan; Decorin; Aggrecan; Cartilage; Osteoarthritis; Proteoglycan; Extracellular matrix; Chemistry; Chondrocyte; Keratan sulfate; Downregulation and upregulation; Immunostaining; Cell biology; Pathology; Medicine; Anatomy; Immunohistochemistry; Biology; Biochemistry; Articular cartilage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005727448,0.0008476833,0.0006335636,0.001514114,0.0003639958,0.0006250392,0.0004816931,0.0009566411,0.001850252],"category_scores_gemma":[0.0002422964,0.0005580981,0.0005731303,0.0004732341,0.0007377659,0.0005679895,0.0003198848,0.001585113,0.0006128676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004738611,"about_ca_system_score_gemma":0.0003650817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009147096,"about_ca_topic_score_gemma":0.001769749,"domain_scores_codex":[0.9993661,0.00009139493,0.00005807853,0.0001772979,0.0001554318,0.0001516492],"domain_scores_gemma":[0.9994065,0.00008710162,0.0001732814,0.00007654533,0.0000725404,0.0001841288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007781184,0.0004527532,0.0001684344,0.00005113263,0.0000101243,0.00006013134,0.00003859623,0.00005765517,0.9975441,0.00007327024,0.0000317434,0.0007339087],"study_design_scores_gemma":[0.0003917965,0.02486671,0.01583274,0.00004928321,0.0001641211,0.0007150795,0.0002750732,0.002082244,0.9514984,0.000220653,0.003856947,0.00004694589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871999,0.003385555,0.005749269,0.0002165838,0.000120246,0.0002849447,0.0007936371,0.0002093387,0.002040338],"genre_scores_gemma":[0.9700761,0.00330266,0.009926043,0.0002138983,0.00007133055,0.0009890199,0.001849235,0.00008948254,0.01348225],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001850252,"threshold_uncertainty_score":0.006189704,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06993573205725709,"score_gpt":0.3527275231263908,"score_spread":0.2827917910691338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}