{"id":"W1570173806","doi":"10.1186/ar1756","title":"Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis","year":2005,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"Murdoch University; Australian Orthopaedic Association","keywords":"Lumican; Biglycan; Decorin; Aggrecan; Cartilage; Osteoarthritis; Proteoglycan; Extracellular matrix; Chemistry; Chondrocyte; Keratan sulfate; Downregulation and upregulation; Immunostaining; Cell biology; Pathology; Medicine; Anatomy; Immunohistochemistry; Biology; Biochemistry; Articular cartilage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001011707,0.0002244985,0.0006168198,0.0004092082,0.0001022412,0.0000285588,0.0001384322,0.0001530424,0.00008854357],"category_scores_gemma":[0.0000330598,0.0002058192,0.0001118955,0.0002885305,0.0003287887,0.0003171978,0.00007852884,0.0003504194,0.000002224647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005815113,"about_ca_system_score_gemma":0.0002835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006279482,"about_ca_topic_score_gemma":0.0004342989,"domain_scores_codex":[0.9971069,0.0003722725,0.0005647607,0.0004985912,0.0008819979,0.0005755411],"domain_scores_gemma":[0.9986451,0.00006880216,0.0001068997,0.000493439,0.0003812968,0.0003044967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008219244,0.0007044889,0.001943989,0.00002359784,0.00001112765,0.00006347569,0.0009904238,0.00003302573,0.8464018,0.0008943984,0.00001154403,0.1481003],"study_design_scores_gemma":[0.01428187,0.007342021,0.00407196,0.0005377429,0.000009695927,0.0000667658,0.000370422,0.001646688,0.9701408,0.0007972638,0.0005395503,0.0001952299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868788,0.0104712,0.0001192366,0.0005267845,0.0000176152,0.001684265,0.00004220334,0.00002681402,0.0002331362],"genre_scores_gemma":[0.9656445,0.006489227,0.02718578,0.00007500117,0.0001028655,0.0003253643,0.00004668374,0.00004353869,0.00008702282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.147905,"threshold_uncertainty_score":0.8393062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06993573205725709,"score_gpt":0.3527275231263908,"score_spread":0.2827917910691338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}