{"id":"W1570428653","doi":"10.1038/mp.2015.65","title":"Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides","year":2015,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Thalamus; Glial fibrillary acidic protein; Caudate nucleus; Neuroscience; Neocortex; Cerebral cortex; Astrocyte; Prefrontal cortex; Cortex (anatomy); Psychology; Cerebellum; Biology; Pathology; Central nervous system; Immunohistochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000623287,0.0001879805,0.0002420643,0.0005160091,0.0002316703,0.0003043599,0.0001607077,0.0001589566,0.0008630686],"category_scores_gemma":[0.000242704,0.0001572637,0.0001606196,0.000231436,0.0003156069,0.00009793845,0.0002168263,0.000193422,0.0001268901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001709834,"about_ca_system_score_gemma":0.0001100905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003937288,"about_ca_topic_score_gemma":0.004987366,"domain_scores_codex":[0.9999379,0.000009177524,0.000005767171,0.00001616351,0.00001410519,0.00001703416],"domain_scores_gemma":[0.9998947,0.000009898502,0.00004672559,0.000006721132,0.0000211041,0.00002083966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003815603,0.00008944704,0.4895399,0.0001676883,0.0004033011,0.002406847,0.001331195,0.0001611847,0.4894704,0.0001848401,0.0003382713,0.01209136],"study_design_scores_gemma":[0.00001098656,0.00007644387,0.9958,0.000004891486,0.00003868309,0.0007490568,0.00036209,0.0001104273,0.00267942,0.00006799688,0.00009690654,0.000003173188],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995222,0.0001528654,0.00008255644,0.00001017113,0.000001866336,0.000001744503,0.00007670971,0.000002582054,0.0001492155],"genre_scores_gemma":[0.9993925,0.00008421009,0.00006743363,0.00001329846,0.00000178871,0.000003369554,0.0001148144,0.000002300612,0.000320278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003937288,"threshold_uncertainty_score":0.007828712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04644680867016101,"score_gpt":0.3447890099720062,"score_spread":0.2983422013018452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}