{"id":"W1572088192","doi":"10.1038/35048603","title":"Rapid exchange of histone H1.1 on chromatin in living human cells","year":2000,"lang":"en","type":"article","venue":"Nature","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":411,"is_retracted":false,"has_abstract":false,"ca_institutions":"Thunder Bay Regional Health Sciences Centre; University of Alberta","funders":"National Medical Research Council; National Institutes of Health; National Health and Medical Research Council; National Heart Foundation of Australia","keywords":"Chromatin; Histone H1; Cell biology; Histone code; Histone; Nucleosome; Histone H2A; Biology; Histone-modifying enzymes; Chromatin remodeling; Chemistry; Biophysics; Molecular biology; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002167884,0.0001012505,0.000286502,0.0002198066,0.0002739261,0.0004468984,0.0002572025,0.0002979948,0.001306477],"category_scores_gemma":[0.0003032537,0.0002203587,0.0001676791,0.0002003364,0.0002966455,0.0004134075,0.0003078819,0.0004050541,0.0004485911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003362462,"about_ca_system_score_gemma":0.0001423265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001009521,"about_ca_topic_score_gemma":0.00111041,"domain_scores_codex":[0.999898,0.00001268775,0.000004335003,0.00004054314,0.00002814768,0.00001640312],"domain_scores_gemma":[0.9998667,0.00005882443,0.00001827852,0.00002595682,0.00001320011,0.00001706581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002768766,0.00001725275,0.001178701,0.00005122166,0.00001446299,0.0001526223,0.0001287828,0.0003799851,0.9897794,0.0007340786,0.0002783407,0.007008225],"study_design_scores_gemma":[0.00006581138,0.0001846565,0.02597183,0.00001092438,0.00003114668,0.0007620531,0.0001947953,0.003090474,0.9610814,0.0009940761,0.007586619,0.00002628512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743873,0.005535969,0.01354286,0.0003123036,0.0001000964,0.00002897292,0.0005214213,0.0001285124,0.00544246],"genre_scores_gemma":[0.9900144,0.00130073,0.0036786,0.0001124002,0.00003666824,0.00003018786,0.0004463436,0.00004086209,0.004339639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306477,"threshold_uncertainty_score":0.00437057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004387501149306223,"score_gpt":0.2474918610576096,"score_spread":0.2431043599083033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}