{"id":"W1573441894","doi":"10.1002/9780470015902.a0002710.pub3","title":"Protein Kinases: Physiological Roles in Cell Signalling","year":2016,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Kinome; Kinase; Crosstalk; Cell biology; Phosphorylation; Biology; Signal transduction; Protein phosphorylation; Signalling; Cell signaling; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004620324,0.001081435,0.0006855413,0.001755378,0.0007568273,0.004262839,0.0006096314,0.001484835,0.02268376],"category_scores_gemma":[0.0004875122,0.0002222042,0.0003621861,0.00277781,0.001567055,0.002499904,0.001615111,0.001448085,0.01870262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008997456,"about_ca_system_score_gemma":0.0009494211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003448522,"about_ca_topic_score_gemma":0.0003129555,"domain_scores_codex":[0.9996362,0.00007366637,0.00003560779,0.00008599044,0.0001235772,0.00004495116],"domain_scores_gemma":[0.9997696,0.00005094366,0.00005047511,0.00002147874,0.00005838481,0.00004904739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003034225,0.0001107639,0.0006329751,0.006364462,0.00004992275,0.0008587764,0.0004686981,0.0007958708,0.02434173,0.1837811,0.09806985,0.6842224],"study_design_scores_gemma":[0.00001185211,0.00002923549,0.0007387648,0.0005069388,0.00001551309,0.0009289249,0.0001326857,0.0001281013,0.002624471,0.02433633,0.970535,0.00001211206],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003783194,0.8424237,0.007149157,0.004783972,0.004147734,0.000051143,0.0009436136,0.0003080701,0.1364095],"genre_scores_gemma":[0.06677372,0.7683663,0.006987925,0.001742484,0.003448746,0.0001386708,0.001248493,0.0001325932,0.1511611],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02268376,"threshold_uncertainty_score":0.07588476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229029483211955,"score_gpt":0.2566125467031591,"score_spread":0.2443222518710396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}