{"id":"W1573447523","doi":"10.1111/j.1474-9726.2010.00601.x","title":"BTG2 antagonizes Pin1 in response to mitogens and telomere disruption during replicative senescence","year":2010,"lang":"en","type":"article","venue":"Aging Cell","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Senescence; Telomere; Biology; Ectopic expression; Cell biology; PIN1; DNA damage; Gene; Cancer research; Genetics; DNA; Isomerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001608652,0.00008994491,0.00006946249,0.00006212507,0.00005276907,0.00001593089,0.00006405773,0.00008894278,0.0000036257],"category_scores_gemma":[0.00005588045,0.0000977186,0.00002033094,0.000116992,0.00003460979,0.000004395841,0.00007398209,0.00009507593,0.000006423224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001942241,"about_ca_system_score_gemma":0.00002790918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003801963,"about_ca_topic_score_gemma":0.0001383078,"domain_scores_codex":[0.9992976,0.0000405821,0.0001152073,0.0003349875,0.000059303,0.0001523689],"domain_scores_gemma":[0.9995655,0.00001305188,0.00004369768,0.0002884823,0.00003136456,0.00005795037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001717681,0.00001474737,0.01546327,0.0000114093,0.000003342467,0.000002139394,0.0002115531,0.00007620527,0.9827027,0.000001632569,0.00002740817,0.001313828],"study_design_scores_gemma":[0.0003068644,0.00004345881,0.1781706,0.00001493648,0.000004003253,0.00001525672,0.00005964711,0.00005462505,0.8195615,0.000007855749,0.001648361,0.0001128403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988615,0.0002022217,0.0001231032,0.0004445215,0.00009801327,0.0001552088,0.00000478275,0.00001218496,0.00009847475],"genre_scores_gemma":[0.9987813,0.00006862468,0.0005821655,0.00003521581,0.0001110249,0.00001335506,0.00001288868,0.00001468344,0.0003807486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1631411,"threshold_uncertainty_score":0.3984849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003410813310025556,"score_gpt":0.2415445500052588,"score_spread":0.2381337366952333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}