{"id":"W1573479840","doi":"10.1111/tra.12131","title":"Microvillus Inclusion Disease: Loss of Myosin Vb Disrupts Intracellular Traffic and Cell Polarity","year":2013,"lang":"en","type":"article","venue":"Traffic","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Medizinische Universität Innsbruck","keywords":"Microvillus; Biology; Enterocyte; Myosin; Cell biology; Cell polarity; Rab; Epithelial polarity; Intracellular; Apical membrane; Endosome; GTPase; Cell; Epithelium; Genetics; Biochemistry; Small intestine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001607302,0.0001959791,0.0003115289,0.0001625731,0.0001726209,0.00002557667,0.0001296402,0.00006769748,0.0003276892],"category_scores_gemma":[0.00004784311,0.0001667432,0.0001254014,0.0001989167,0.0002543268,0.0001170311,0.0003905534,0.0001896619,0.00009232235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006202706,"about_ca_system_score_gemma":0.0001372347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007381507,"about_ca_topic_score_gemma":0.00001028284,"domain_scores_codex":[0.9983969,0.00006396663,0.0002831295,0.0003481877,0.0004943032,0.0004134561],"domain_scores_gemma":[0.9986563,0.00004666673,0.00006668502,0.0003877536,0.0000993149,0.0007432271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004231579,0.01691454,0.01813788,0.01624102,0.0007229278,0.003462964,0.007615407,0.001502141,0.3417182,0.0007221983,0.04618711,0.542544],"study_design_scores_gemma":[0.02374264,0.002777184,0.8110071,0.001336884,0.001535624,0.000157601,0.001535641,0.04710389,0.01951145,0.0002920608,0.0888676,0.002132291],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876287,0.009020897,0.00003265313,0.001831169,0.00005169688,0.001047154,0.00002663891,0.00007809882,0.0002829786],"genre_scores_gemma":[0.996629,0.002017533,0.0001566979,0.0001299368,0.000069173,0.00002961305,0.00008669246,0.00002827804,0.0008530785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7928693,"threshold_uncertainty_score":0.6799592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007568427316262382,"score_gpt":0.2466982422309809,"score_spread":0.2391298149147185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}