{"id":"W1574164457","doi":"10.1002/j.1939-4640.2004.tb02828.x","title":"Inhibitors of Phosphoinositide 3‐Kinase, LY294002 and Wortmannin, Affect Sperm Capacitation and Associated Phosphorylation of Proteins Differently: Ca<sup>2+</sup>‐Dependent Divergences","year":2004,"lang":"en","type":"article","venue":"Journal of Andrology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Hôpital Saint-François d'Assise; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Wortmannin; Capacitation; Phosphoinositide 3-kinase; LY294002; Phosphorylation; Cell biology; Sperm; Kinase; Chemistry; Pi; Affect (linguistics); Phosphatidylinositol; Biology; Protein kinase B; Biochemistry; Genetics; Psychology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418956,0.0004981032,0.0004051151,0.0001899279,0.0001455014,0.0002426103,0.0003775593,0.0003450288,0.001801631],"category_scores_gemma":[0.0001204169,0.0001213336,0.0003557458,0.000240164,0.0002871414,0.0002384146,0.000182608,0.0005864803,0.0003924918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003888997,"about_ca_system_score_gemma":0.0004208271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007871568,"about_ca_topic_score_gemma":0.001478943,"domain_scores_codex":[0.9998257,0.0000238772,0.00002246795,0.0000325129,0.00004372515,0.00005174191],"domain_scores_gemma":[0.9998977,0.00002271456,0.00002170583,0.000009742681,0.0000164503,0.0000316831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003990954,0.00005144361,0.0001029736,0.00004916609,0.000007861631,0.0000603682,0.0000104725,0.00005957976,0.9980895,0.0000498046,0.00003540254,0.001084337],"study_design_scores_gemma":[0.0000292798,0.0004105613,0.003201491,0.0000016538,0.00001071501,0.0001103684,0.00001120413,0.0005393541,0.9947973,0.00001606053,0.0008683588,0.000003736818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894978,0.004706393,0.001912777,0.0002078162,0.00009831126,0.00007985077,0.0006037943,0.0001607219,0.002732558],"genre_scores_gemma":[0.992019,0.002023441,0.001815656,0.00009608247,0.00002442431,0.0001056293,0.0008427364,0.0000258597,0.003047062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001801631,"threshold_uncertainty_score":0.006027102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01354768007659046,"score_gpt":0.2519624021332375,"score_spread":0.238414722056647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}