{"id":"W1574416391","doi":"10.1186/ar836","title":"PPARγ ligands inhibit catabolic and inflammatory responses in articular joint cells","year":2003,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; Deutsche Forschungsgemeinschaft; Lupus Research Alliance; Wellcome Trust","keywords":"Nitric oxide; Chemistry; Peroxisome proliferator-activated receptor; Receptor; Nitric oxide synthase; Nuclear receptor; Tumor necrosis factor alpha; Internal medicine; Transcription factor; Endocrinology; Arthritis; Inflammation; Catabolism; Cell biology; Biochemistry; Biology; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002738149,0.0005304395,0.0004938467,0.0005146139,0.0002438322,0.0003710823,0.000278636,0.000397293,0.005759992],"category_scores_gemma":[0.0002619777,0.0002580728,0.0005621135,0.0003354005,0.0003389468,0.0001734786,0.0003603045,0.001103113,0.001807206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002369622,"about_ca_system_score_gemma":0.0006754607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001263526,"about_ca_topic_score_gemma":0.002604689,"domain_scores_codex":[0.9996247,0.00006994281,0.00005240353,0.00004217679,0.00009577753,0.0001149076],"domain_scores_gemma":[0.9998084,0.00002573689,0.00003913737,0.00002636334,0.00003561969,0.00006477738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002338802,0.0003962614,0.0002227704,0.0003684879,0.00002680997,0.0001669791,0.00008115885,0.0002145617,0.9857146,0.000166148,0.0006066235,0.009696752],"study_design_scores_gemma":[0.0007394229,0.006655805,0.007014656,0.00009770379,0.0001371082,0.0008385689,0.0004120592,0.001191534,0.9549868,0.0003897514,0.02749963,0.00003703127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9484262,0.02666809,0.006917713,0.001278163,0.0006723315,0.0001903257,0.001623375,0.0007005354,0.01352328],"genre_scores_gemma":[0.955187,0.01195618,0.002821226,0.0008353975,0.0001350386,0.0002349823,0.002010714,0.00005998404,0.0267595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005759992,"threshold_uncertainty_score":0.01926905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02599467372735991,"score_gpt":0.2975147894287082,"score_spread":0.2715201157013483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}