{"id":"W1574759345","doi":"10.1038/pcan.2015.17","title":"Extracellular vesicles such as prostate cancer cell fragments as a fluid biopsy for prostate cancer","year":2015,"lang":"en","type":"review","venue":"Prostate Cancer and Prostatic Diseases","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Prostate cancer; Liquid biopsy; Prostate; Medicine; Vesicle; Microvesicles; Extracellular vesicle; Biomarker; PCA3; Exocytosis; Cancer research; Biomarker discovery; Pathology; Circulating tumor cell; Cancer; Internal medicine; Chemistry; microRNA; Proteomics; Metastasis; Membrane; Secretion; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006385898,0.0007779688,0.001349387,0.001651717,0.0002521961,0.001219383,0.000630045,0.001373035,0.002054967],"category_scores_gemma":[0.0007663563,0.0003157134,0.0004207146,0.001238998,0.0006378739,0.001523601,0.0008209763,0.001627269,0.001149238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006486641,"about_ca_system_score_gemma":0.0007736797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009004484,"about_ca_topic_score_gemma":0.001832582,"domain_scores_codex":[0.9998118,0.00003434254,0.00002542494,0.00003124322,0.00007851294,0.00001867578],"domain_scores_gemma":[0.9997619,0.0001254777,0.00003281669,0.000007837769,0.00005485822,0.00001723641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000123295,0.00005817522,0.0002276696,0.0139968,0.00008488923,0.0003304713,0.00006797675,0.0005064608,0.005392421,0.009420948,0.0273976,0.9423934],"study_design_scores_gemma":[0.00001546339,0.00005603965,0.0004809969,0.002052569,0.0000904728,0.001352116,0.0000634734,0.000208485,0.002106542,0.002648497,0.9908985,0.00002686003],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001193835,0.9988192,0.0001916631,0.000165751,0.0001827948,0.000003488565,0.00001299347,0.000004521971,0.0005001931],"genre_scores_gemma":[0.001192035,0.99731,0.0003071995,0.000190005,0.0001526777,0.000006694896,0.00002975514,0.000002142527,0.0008094976],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002054967,"threshold_uncertainty_score":0.006874502,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02236561793606962,"score_gpt":0.3375827562394811,"score_spread":0.3152171383034115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}