{"id":"W1574816650","doi":"10.1096/fasebj.28.1_supplement.677.11","title":"Human Ca <sub>V</sub> 1.2/Ca <sub>V</sub> 3.x channels mediate paradoxical vasomotor responses in the human cerebral circulation (677.11)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Cerebral circulation; Electrical impedance myography; Patch clamp; Cerebral arteries; Electrophysiology; Gene isoform; Vasomotor; Chemistry; Cerebral blood flow; Vascular smooth muscle; Western blot; Biophysics; Anatomy; Internal medicine; Neuroscience; Endocrinology; Vasodilation; Biology; Medicine; Smooth muscle; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001148522,0.0001408688,0.0001562035,0.0001641188,0.0001210348,0.0002963922,0.0001169545,0.0002674109,0.001470937],"category_scores_gemma":[0.000354743,0.00008188832,0.0001570246,0.000117611,0.0002413407,0.0001769502,0.0001136137,0.0002344877,0.0002883963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143153,"about_ca_system_score_gemma":0.000123756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009327853,"about_ca_topic_score_gemma":0.001116154,"domain_scores_codex":[0.9999503,0.000004330552,0.000003708426,0.00001869923,0.00001026863,0.00001267928],"domain_scores_gemma":[0.999876,0.00002562208,0.00005316706,0.00001305519,0.00001385483,0.00001830719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008008771,0.000033137,0.03437858,0.00008514716,0.00005010467,0.001231288,0.0002953489,0.00009912554,0.9404857,0.00037123,0.0007011109,0.02146828],"study_design_scores_gemma":[0.00009975239,0.000613562,0.7732271,0.0000389708,0.0001485795,0.0135956,0.0003749755,0.001637933,0.2010434,0.001095661,0.008087985,0.00003655431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931249,0.001350181,0.0040197,0.0001562464,0.00002769663,0.00002083289,0.0003196882,0.00009873885,0.0008821395],"genre_scores_gemma":[0.9976242,0.0005097968,0.0008656773,0.00009715891,0.00002337231,0.0000139252,0.0001872351,0.00001044158,0.0006680233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001470937,"threshold_uncertainty_score":0.004920721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01975334516948758,"score_gpt":0.2566209652445344,"score_spread":0.2368676200750469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}