{"id":"W1574902133","doi":"10.1038/nri1257","title":"T-cell development made simple","year":2004,"lang":"en","type":"review","venue":"Nature reviews. Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":315,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Women's College Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Lymphopoiesis; Cell biology; Thymocyte; Extracellular matrix; Function (biology); Biology; Stem cell; Cellular differentiation; Receptor; Chemistry; T cell; Haematopoiesis; Immunology; Biochemistry; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001343155,0.001664488,0.002408924,0.001121149,0.000599511,0.001885008,0.001553458,0.002963808,0.005444907],"category_scores_gemma":[0.0008472828,0.0005859796,0.0006180992,0.001151416,0.002107081,0.003537231,0.001356299,0.006083395,0.005310467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001491556,"about_ca_system_score_gemma":0.001313438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000756097,"about_ca_topic_score_gemma":0.001308558,"domain_scores_codex":[0.9996692,0.00007045823,0.00003135579,0.00006774699,0.0001166925,0.00004464422],"domain_scores_gemma":[0.9996289,0.000161794,0.00002565232,0.00002527016,0.0001154902,0.00004290944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002466648,0.0001127355,0.0001614209,0.00819052,0.00008546748,0.0004306983,0.00008850268,0.0007616428,0.009154592,0.05381255,0.1537921,0.7731631],"study_design_scores_gemma":[0.00002708754,0.00004607241,0.0001033369,0.0006219895,0.00002194705,0.0004088306,0.0000227396,0.00006308858,0.0008048693,0.006446364,0.9914235,0.00001024093],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001776188,0.986964,0.00123005,0.002266096,0.004702907,0.00001182943,0.00002224614,0.00003908992,0.00458608],"genre_scores_gemma":[0.001698791,0.9869467,0.0009278103,0.002537681,0.001860326,0.00002742686,0.00004465301,0.00001002989,0.005946589],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005444907,"threshold_uncertainty_score":0.01821506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05349645198295755,"score_gpt":0.3988182439844727,"score_spread":0.3453217920015151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}