{"id":"W1575075264","doi":"10.1002/bdrb.21132","title":"Exposure‐Based Validation List for Developmental Toxicity Screening Assays","year":2014,"lang":"en","type":"article","venue":"Birth Defects Research Part B Developmental and Reproductive Toxicology","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Developmental toxicity; Toxicity; Toxicokinetics; In vivo; Chemical compound; Toxicology; Toxicodynamics; Biology; Medicine; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003310864,0.0002934641,0.0003499632,0.0001461914,0.0009610708,0.0000850851,0.0002871981,0.0001478954,0.0004631714],"category_scores_gemma":[0.002599837,0.0002430795,0.00007997173,0.0004177141,0.0007629906,0.0002233185,0.0005470675,0.0003545905,0.0001094411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003017555,"about_ca_system_score_gemma":0.00008029356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007892297,"about_ca_topic_score_gemma":0.00009943877,"domain_scores_codex":[0.9963091,0.0005237627,0.000391798,0.001263677,0.0005754528,0.000936182],"domain_scores_gemma":[0.9983028,0.0009694262,0.000113238,0.0002433802,0.0000916197,0.0002795125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005433372,0.0006581009,0.2547052,0.000189594,0.00009035892,0.00001829297,0.0005534508,0.0002357955,0.6554155,0.0004439671,0.01846323,0.06868318],"study_design_scores_gemma":[0.001860936,0.0009460236,0.08408102,0.00006852565,0.00001453962,0.0000767059,0.0003095568,0.0004478582,0.7163119,0.001149882,0.1940916,0.0006414665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98998,0.00006038874,0.001250093,0.0008425887,0.0001689696,0.001190969,0.00001670361,0.00008998177,0.006400275],"genre_scores_gemma":[0.9712368,0.0000254882,0.02604751,0.0003004485,0.0002415587,0.0004137417,0.00007058621,0.00003801696,0.001625826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1756284,"threshold_uncertainty_score":0.9912496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0629585595587123,"score_gpt":0.3789734156113758,"score_spread":0.3160148560526634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}