{"id":"W1575966267","doi":"10.4049/jimmunol.0802387","title":"Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":535,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal; Montreal General Hospital; University of Manitoba; Montreal Children's Hospital; Montreal Neurological Institute and Hospital; McGill University; Christie (Canada)","funders":"","keywords":"Proinflammatory cytokine; Asthma; Cytokine; Dexamethasone; Medicine; Laser capture microdissection; Tumor necrosis factor alpha; Immunology; Immunocytochemistry; Blot; Interleukin 8; Lung; Inflammation; Messenger RNA; Internal medicine; Gene expression; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001829365,0.0002426628,0.000249407,0.0005061342,0.0002142061,0.0002043857,0.0001049346,0.0004577872,0.001516811],"category_scores_gemma":[0.0002848043,0.000234796,0.000180286,0.0002733779,0.0003145813,0.0001343613,0.000308486,0.0004320181,0.0003216901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007041806,"about_ca_system_score_gemma":0.00007718319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003617475,"about_ca_topic_score_gemma":0.0004541971,"domain_scores_codex":[0.9998512,0.00004000161,0.00001193518,0.0000297782,0.00003679207,0.00003018121],"domain_scores_gemma":[0.9997332,0.00004342242,0.00006611834,0.00002417795,0.00002877633,0.0001043505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001110883,0.00005229312,0.05743297,0.0001553821,0.00003398958,0.001309514,0.0001769185,0.00003812291,0.9362031,0.00002399523,0.0001121216,0.003350733],"study_design_scores_gemma":[0.00005679068,0.001360809,0.9579907,0.00002791748,0.00006475131,0.007112694,0.0002880303,0.0003077686,0.03152992,0.0001101982,0.001139714,0.00001072395],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961538,0.002758328,0.0003913551,0.00005581311,0.000008399545,0.00001647637,0.0001359606,0.00001074879,0.0004690733],"genre_scores_gemma":[0.9985052,0.0006885711,0.0003134108,0.00004187272,0.00002326185,0.00001530425,0.000213357,0.000002613349,0.0001965664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001516811,"threshold_uncertainty_score":0.005074263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01104994180506644,"score_gpt":0.2299390153242198,"score_spread":0.2188890735191533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}