{"id":"W1576255678","doi":"10.1002/9780470571224.pse200","title":"Introduction to Clinical Trials","year":2010,"lang":"en","type":"other","venue":"Pharmaceutical Sciences Encyclopedia","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Clinical trial; Drug development; Drug trial; Disease; Medicine; Intensive care medicine; Drug; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03714502,0.001872097,0.001549856,0.004659778,0.001144834,0.008370216,0.00294454,0.005111435,0.07712513],"category_scores_gemma":[0.09237329,0.0009402076,0.001431168,0.003957491,0.005352083,0.006404828,0.00401881,0.01053543,0.04042456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00416703,"about_ca_system_score_gemma":0.008739094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001303776,"about_ca_topic_score_gemma":0.001018936,"domain_scores_codex":[0.9655591,0.02198163,0.003280206,0.002068066,0.006558056,0.000553022],"domain_scores_gemma":[0.8969096,0.06889073,0.003983748,0.008482165,0.01735214,0.004381605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002154059,0.0001187535,0.0002528928,0.003142607,0.00004832702,0.0001282128,0.0002567212,0.0006117582,0.0003297829,0.2037683,0.392429,0.3986982],"study_design_scores_gemma":[0.00004676119,0.00008894947,0.0002556343,0.002825559,0.00001428142,0.0003006798,0.00006929434,0.0002923642,0.0001475153,0.06761862,0.9283182,0.00002208231],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0009491266,0.1793902,0.2619128,0.1521313,0.03468288,0.004704663,0.005547318,0.00300151,0.3576802],"genre_scores_gemma":[0.03410218,0.2674266,0.3230554,0.1222888,0.05030366,0.01403816,0.006066173,0.00240246,0.1803165],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.07712513,"threshold_uncertainty_score":0.2580093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7502160516990037,"score_gpt":0.6875786571471404,"score_spread":0.06263739455186335,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}