{"id":"W1576482041","doi":"10.1016/s0076-6879(03)01035-8","title":"Direct Fluorescence-Based Detection Methods for Multivalent Interactions","year":2003,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kimberly-Clark (Canada)","funders":"","keywords":"Ligand (biochemistry); Receptor; Chemistry; Fluorescence; Binding site; Biophysics; Dimer; Combinatorial chemistry; Biochemistry; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001044919,0.001362275,0.0007814242,0.00095674,0.0006435071,0.0008628786,0.002003331,0.001239907,0.004835046],"category_scores_gemma":[0.00136993,0.000866312,0.0005008529,0.0005106739,0.000820561,0.00118301,0.00174808,0.003007181,0.003271486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008453022,"about_ca_system_score_gemma":0.0004376416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004674706,"about_ca_topic_score_gemma":0.001074936,"domain_scores_codex":[0.9989434,0.0001703628,0.00003685681,0.0002890488,0.0004332744,0.0001270836],"domain_scores_gemma":[0.999161,0.0003389362,0.00009347763,0.000161634,0.0001607356,0.00008420055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000120762,0.00005805961,0.0001301826,0.0002883468,0.00001909461,0.00004209944,0.00007488336,0.0001085947,0.974187,0.002030076,0.0009107343,0.02203028],"study_design_scores_gemma":[0.00002414742,0.00006347497,0.0001992453,0.0000116955,0.00001357792,0.0001947697,0.00001383475,0.001705913,0.9932382,0.0004865737,0.00403343,0.00001501004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1219276,0.006251797,0.8556909,0.0005209127,0.0003432236,0.0004857582,0.0006535246,0.002195518,0.01193076],"genre_scores_gemma":[0.4517199,0.005749404,0.5078741,0.0006853985,0.0001404329,0.001574868,0.001045159,0.0004796343,0.03073104],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004835046,"threshold_uncertainty_score":0.01617479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04754321766855892,"score_gpt":0.43630372512145,"score_spread":0.3887605074528911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}