{"id":"W1576517042","doi":"10.1111/j.1365-2567.2011.03425.x","title":"Induction of latency‐associated peptide (transforming growth factor‐β<sub>1</sub>) expression on CD4<sup>+</sup> T cells reduces Toll‐like receptor 4 ligand‐induced tumour necrosis factor‐α production in a transforming growth factor‐β‐dependent manner","year":2011,"lang":"en","type":"article","venue":"Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Transforming growth factor; Latency (audio); Receptor; Toll-like receptor; Tumor necrosis factor alpha; Biology; Cell biology; Peptide; Cancer research; Ligand (biochemistry); Molecular biology; Chemistry; Immunology; Genetics; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005587668,0.0009437354,0.001317186,0.001212427,0.0005426776,0.00003618264,0.0007299019,0.001621279,0.0003884941],"category_scores_gemma":[0.0002894013,0.0008634057,0.0004582145,0.0006946542,0.0004488078,0.001004379,0.0001030321,0.001732673,0.0002142214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000451637,"about_ca_system_score_gemma":0.0002377754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096975,"about_ca_topic_score_gemma":0.00007786951,"domain_scores_codex":[0.9943438,0.001228049,0.001660378,0.001159891,0.0002317623,0.001376141],"domain_scores_gemma":[0.997897,0.000291135,0.000770516,0.0006252048,0.0003565469,0.00005963112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004815483,0.0011145,0.001035326,0.00006665911,0.0005989514,0.00001109518,0.02426778,0.000008108073,0.9597943,0.00003252181,0.00008069421,0.00817457],"study_design_scores_gemma":[0.003471142,0.001818164,0.02279077,0.0005734157,0.00006774371,0.00007276824,0.002434394,0.000001483682,0.9676145,0.0001191304,0.0001976973,0.0008387758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992974,0.00174682,0.00003187448,0.0001715563,0.003118526,0.001341647,0.000150475,0.0002586305,0.0002064184],"genre_scores_gemma":[0.9961454,0.002800967,0.00003932289,0.00005531015,0.00006937275,0.0001672637,0.0001587517,0.0001350234,0.0004285577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02183339,"threshold_uncertainty_score":0.9996748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02244392031689133,"score_gpt":0.2246143263308935,"score_spread":0.2021704060140021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}