{"id":"W1576539828","doi":"10.25011/cim.v31i4.4799","title":"THE P53 FAMILY MEMBER, P63, REGULATES NEURAL PRECURSOR CELL SURVIVAL DURING CORTICAL DEVELOPMENT","year":2008,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Neurogenesis; Gene knockdown; Cre recombinase; Neural stem cell; Biology; Cell biology; Programmed cell death; Embryonic stem cell; Apoptosis; Cell growth; Small hairpin RNA; Stem cell; Neuroscience; Genetically modified mouse; Transgene; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001001719,0.0002709342,0.0001658979,0.0003048823,0.0002447578,0.0003510547,0.000177395,0.0002559837,0.0009195572],"category_scores_gemma":[0.000177613,0.0001008928,0.0001353391,0.0001197049,0.0002236871,0.0002013874,0.0002081665,0.000422751,0.0003617933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003372867,"about_ca_system_score_gemma":0.0002227434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005892995,"about_ca_topic_score_gemma":0.0008283408,"domain_scores_codex":[0.9999177,0.000008075796,0.00000615742,0.00001908445,0.00002431895,0.00002461461],"domain_scores_gemma":[0.9998272,0.00001733166,0.00005722233,0.00001241163,0.00003625716,0.00004963016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000852895,0.00001498502,0.0008864228,0.00003381938,0.000002933691,0.0001570925,0.00001828563,0.00003990567,0.9957309,0.00005014514,0.00005055009,0.002929518],"study_design_scores_gemma":[0.00001552478,0.0001649309,0.04008251,0.0000185601,0.00002120712,0.0005694102,0.00006077121,0.0007254325,0.9559662,0.0001646803,0.002206079,0.000004729773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888806,0.004491127,0.00414644,0.0001095917,0.00002855699,0.0000247139,0.0002867843,0.0001285672,0.001903539],"genre_scores_gemma":[0.9956363,0.001523137,0.0009894433,0.00002490173,0.00001074344,0.00001929407,0.0001968932,0.00001240756,0.001586892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009195572,"threshold_uncertainty_score":0.003076196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1518619222067522,"score_gpt":0.3537460369431106,"score_spread":0.2018841147363585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}