{"id":"W1577035833","doi":"10.1111/j.1365-2958.2005.04802.x","title":"CesT is a multi‐effector chaperone and recruitment factor required for the efficient type III secretion of both LEE‐ and non‐LEE‐encoded effectors of enteropathogenic <i>Escherichia coli</i>","year":2005,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Effector; Type three secretion system; Secretion; Chaperone (clinical); Biology; Cell biology; Cytoplasm; Escherichia coli; Enteropathogenic Escherichia coli; Immunoprecipitation; Virulence; Genetics; Cell culture; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117201,0.0003624166,0.0002595549,0.0001660252,0.0002148144,0.0003383328,0.0001576655,0.0002769864,0.0007664987],"category_scores_gemma":[0.0002314025,0.0001260648,0.0003618968,0.0001533836,0.000177807,0.0001712393,0.0002866258,0.000367033,0.0006411292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005001427,"about_ca_system_score_gemma":0.0003901577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007135624,"about_ca_topic_score_gemma":0.0007458786,"domain_scores_codex":[0.9998652,0.00001607063,0.00001498557,0.00002958023,0.00004685553,0.00002732478],"domain_scores_gemma":[0.9998581,0.00001333827,0.00003276453,0.00001580093,0.00003224343,0.00004759002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007171654,0.00001510994,0.0004315833,0.00001996848,0.000003840586,0.00009922142,0.000008843281,0.00003973119,0.9986346,0.00004323796,0.00005838063,0.00057379],"study_design_scores_gemma":[0.0000137788,0.00008231698,0.01503103,0.000004785601,0.00001032478,0.0007031795,0.00002570098,0.001461475,0.9797271,0.00002861465,0.002904391,0.000007348261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937834,0.0005250218,0.003916205,0.0001218438,0.00003157304,0.00003459887,0.0006920432,0.0001322847,0.0007629532],"genre_scores_gemma":[0.9903577,0.0002550418,0.003736854,0.00009229069,0.0000157117,0.00002520079,0.002857705,0.0000594957,0.002599998],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007664987,"threshold_uncertainty_score":0.00362879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110937484185746,"score_gpt":0.2831018203648266,"score_spread":0.2619924455229691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}