{"id":"W1577035833","doi":"10.1111/j.1365-2958.2005.04802.x","title":"CesT is a multi‐effector chaperone and recruitment factor required for the efficient type III secretion of both LEE‐ and non‐LEE‐encoded effectors of enteropathogenic <i>Escherichia coli</i>","year":2005,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Effector; Type three secretion system; Secretion; Chaperone (clinical); Biology; Cell biology; Cytoplasm; Escherichia coli; Enteropathogenic Escherichia coli; Immunoprecipitation; Virulence; Genetics; Cell culture; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003142984,0.000250912,0.0003779508,0.00004984968,0.00009963173,0.000009778772,0.0001864092,0.0001904371,0.000006706714],"category_scores_gemma":[0.00009354029,0.0001888629,0.0001181709,0.0001076036,0.0003961631,0.000003395145,0.0002715597,0.0001005796,9.45956e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002507945,"about_ca_system_score_gemma":0.00005743865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003001834,"about_ca_topic_score_gemma":0.00002776325,"domain_scores_codex":[0.9986098,0.0001974401,0.0003182492,0.0004630958,0.00006906163,0.0003423776],"domain_scores_gemma":[0.9991679,0.000093661,0.0001895884,0.0003351942,0.0001446666,0.00006899416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000454651,0.0001451168,0.001007975,0.0001483623,0.0002024818,9.445088e-7,0.000309344,0.0000478717,0.9970053,0.000004454569,0.00008900298,0.0005844262],"study_design_scores_gemma":[0.002380872,0.001637326,0.002491753,0.00003321782,0.00008054407,0.000008123162,0.00004988807,0.001648909,0.9878914,5.927123e-7,0.003587475,0.0001898624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806893,0.008459891,0.008659755,0.0001441615,0.00009404114,0.001754765,0.0001815269,0.000006922573,0.000009643597],"genre_scores_gemma":[0.9960077,0.000778947,0.002550644,0.0002560792,0.00003934301,0.0001947451,0.00007969483,0.0000298195,0.00006304896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01531838,"threshold_uncertainty_score":0.7701606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110937484185746,"score_gpt":0.2831018203648266,"score_spread":0.2619924455229691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}