{"id":"W1577728657","doi":"10.1002/arch.21066","title":"EFFECTS OF GENETIC KNOCK‐DOWN OF ORGANIC ANION TRANSPORTER GENES ON SECRETION OF FLUORESCENT ORGANIC IONS BY MALPIGHIAN TUBULES OF <scp>D</scp>rosophila melanogaster","year":2012,"lang":"en","type":"article","venue":"Archives of Insect Biochemistry and Physiology","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Secretion; Transporter; Biology; Efflux; P-glycoprotein; Organic anion-transporting polypeptide; Organic anion transporter 1; Gene expression; Biochemistry; Molecular biology; ATP-binding cassette transporter; Fluorescence; Green fluorescent protein; Gene; Cell biology; Multiple drug resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007705912,0.0002326289,0.0005754937,0.000111917,0.00005406493,0.00000102358,0.0003270742,0.0001971328,0.00004145048],"category_scores_gemma":[0.0002103044,0.0001951733,0.0001417305,0.0001781899,0.001469914,0.00004450924,0.0001097744,0.0002331314,0.000001335794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004026383,"about_ca_system_score_gemma":0.000045497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008563461,"about_ca_topic_score_gemma":6.327912e-7,"domain_scores_codex":[0.9982815,0.0003647009,0.0005127239,0.0003776734,0.0001185894,0.0003448503],"domain_scores_gemma":[0.9977943,0.00131945,0.0004041927,0.0003466408,0.00004251755,0.00009288748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003250846,0.0006620199,0.005794865,0.001327109,0.00005156502,8.851019e-7,0.0005861956,0.000003065598,0.9909788,0.00008443969,0.00002545104,0.0001605616],"study_design_scores_gemma":[0.0005454677,0.001068329,0.1404948,0.0001031672,0.00003591384,0.00001166168,0.00002828631,0.000009522302,0.8572266,0.0004015785,0.000008295502,0.00006639693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986782,0.000721996,0.00001967815,0.00001606087,0.00007677494,0.0002187281,0.0001518559,0.000008297345,0.0001083782],"genre_scores_gemma":[0.9987081,0.001050436,0.00004586014,0.00003923824,0.00004949737,0.000008869386,0.00005142024,0.00001830666,0.0000282267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1346999,"threshold_uncertainty_score":0.7958935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00911038382068502,"score_gpt":0.2204175085444129,"score_spread":0.2113071247237279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}