{"id":"W1577728657","doi":"10.1002/arch.21066","title":"EFFECTS OF GENETIC KNOCK‐DOWN OF ORGANIC ANION TRANSPORTER GENES ON SECRETION OF FLUORESCENT ORGANIC IONS BY MALPIGHIAN TUBULES OF <scp>D</scp>rosophila melanogaster","year":2012,"lang":"en","type":"article","venue":"Archives of Insect Biochemistry and Physiology","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Secretion; Transporter; Biology; Efflux; P-glycoprotein; Organic anion-transporting polypeptide; Organic anion transporter 1; Gene expression; Biochemistry; Molecular biology; ATP-binding cassette transporter; Fluorescence; Green fluorescent protein; Gene; Cell biology; Multiple drug resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001427804,0.000655756,0.0002296626,0.0003399577,0.0002193046,0.0003839799,0.000310699,0.0003676211,0.001451855],"category_scores_gemma":[0.000157571,0.0002876697,0.0003005441,0.0001480182,0.0003963107,0.0002301027,0.0002711233,0.0006963219,0.0003993838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000621354,"about_ca_system_score_gemma":0.0002812913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002894178,"about_ca_topic_score_gemma":0.004719088,"domain_scores_codex":[0.9998223,0.00002887044,0.00003250327,0.00004601452,0.00004470663,0.00002553314],"domain_scores_gemma":[0.9996141,0.0001029917,0.0001217933,0.00003890406,0.00003038028,0.00009184037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003127793,0.000009044024,0.00008796557,0.000014858,0.000003546565,0.00003345745,0.00000872105,0.00002686035,0.9995585,0.00002669232,0.00001101351,0.000188075],"study_design_scores_gemma":[0.0000221052,0.0001265941,0.006224826,0.000006231938,0.00002144994,0.0001083906,0.00004183089,0.0008456087,0.991317,0.00002385331,0.001252594,0.000009419246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964515,0.0003364688,0.001264789,0.00008578633,0.00002100074,0.00004169783,0.0007549108,0.0001159785,0.0009278125],"genre_scores_gemma":[0.9897327,0.0006087197,0.003304573,0.0001127266,0.000008787173,0.00008272127,0.001029752,0.0001658088,0.004954303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002894178,"threshold_uncertainty_score":0.00575465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00911038382068502,"score_gpt":0.2204175085444129,"score_spread":0.2113071247237279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}