{"id":"W15778447","doi":"10.1016/j.cct.2011.01.016","title":"Data withdrawal in randomized controlled trials: Defining the problem and proposing solutions","year":2011,"lang":"en","type":"review","venue":"Contemporary Clinical Trials","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences; Population Health Research Institute; University of Waterloo; McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Missing data; Randomized controlled trial; Medicine; Data collection; Imputation (statistics); Research ethics; Research design; Legislation; Psychiatry; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","metaepi_broad","sts","research_integrity"],"consensus_categories":["metaresearch","research_integrity"],"category_scores_codex":[0.7898167,0.001030279,0.06629094,0.0005584129,0.0003296942,0.0003207459,0.002027486,0.003306568,0.0001803029],"category_scores_gemma":[0.9112148,0.0004517159,0.007828109,0.0006644353,0.003476251,0.0002818948,0.002244678,0.01099199,0.0001046519],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009640874,"about_ca_system_score_gemma":0.01486822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001694129,"about_ca_topic_score_gemma":0.0001082055,"domain_scores_codex":[0.5829838,0.3336736,0.07354896,0.004855418,0.003074469,0.001863761],"domain_scores_gemma":[0.009589664,0.9707438,0.01371928,0.004377653,0.0007571507,0.0008124987],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.1958587,0.0008469667,0.00006105337,0.01183928,0.008574644,0.0001400928,0.00007607572,3.8275e-8,6.861639e-8,0.03885984,0.005539031,0.7382042],"study_design_scores_gemma":[0.379072,0.0004201092,0.00000157431,0.05878147,0.01128768,0.00003639768,0.00004306603,0.00007370888,3.087812e-8,0.02390341,0.5259716,0.000408911],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000001026318,0.9408883,0.0002264449,0.003617031,0.00106037,0.04022698,0.0003919611,0.00009761222,0.0134902],"genre_scores_gemma":[0.0001088791,0.9900734,0.00249813,0.0005209467,0.001819492,0.002517919,0.0005828324,0.0001462597,0.001732144],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7377953,"threshold_uncertainty_score":0.9997935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9355699870092793,"score_gpt":0.6971668011665915,"score_spread":0.2384031858426878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}