{"id":"W1577854588","doi":"10.18433/j3801t","title":"Tacrine Sinusoidal Uptake and Biliary Excretion in Sandwich-Cultured Primary Rat Hepatocytes","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences","keywords":"Tacrine; Excretion; Chemistry; Primary (astronomy); Internal medicine; Pharmacology; Endocrinology; Medicine; Biochemistry; Physics; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002851817,0.0002821295,0.0003980537,0.0001330601,0.0001369739,0.0002602795,0.0002190771,0.0002254267,0.001038008],"category_scores_gemma":[0.0001127701,0.0001858594,0.0004193708,0.0001689882,0.0001570187,0.0002257078,0.00016203,0.0003893868,0.000766685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002301202,"about_ca_system_score_gemma":0.0002021624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001790592,"about_ca_topic_score_gemma":0.002773708,"domain_scores_codex":[0.9997229,0.00004765361,0.00003380894,0.00007449727,0.00006757976,0.00005355291],"domain_scores_gemma":[0.999856,0.00002789834,0.00002646309,0.00002975231,0.00004117009,0.00001872809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002157293,0.00002967449,0.0003810694,0.00005366948,0.00000866731,0.00007621972,0.00002412164,0.00006635923,0.9980026,0.00004438926,0.00003452683,0.001062956],"study_design_scores_gemma":[0.00001463572,0.0007084025,0.004584465,0.000004145143,0.00002950999,0.0002481188,0.00004670933,0.001440475,0.9920633,0.00002139217,0.0008318484,0.000006870231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802729,0.004272749,0.01078793,0.0001690511,0.00008303851,0.00004800165,0.0009364248,0.0002101162,0.003219809],"genre_scores_gemma":[0.98449,0.001569724,0.008594406,0.00007529279,0.00002259501,0.00006114083,0.0009376387,0.00002559535,0.004223611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790592,"threshold_uncertainty_score":0.003560305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0352633289505014,"score_gpt":0.3450643387255106,"score_spread":0.3098010097750092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}