{"id":"W1578691566","doi":"10.1002/9780470285251.ch9","title":"Structure, Mechanism, and Regulation of Cytochromes P450","year":2007,"lang":"en","type":"other","venue":"","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Cytochrome P450; Mechanism (biology); SUPERFAMILY; Cytochrome P450 reductase; Cytochrome; Reading (process); Chemistry; Biology; Gene; Biochemistry; Cytochrome b; Enzyme; Political science; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002108943,0.000405861,0.0003290969,0.0005708193,0.0002635857,0.0007267781,0.0004179645,0.0005721034,0.02502717],"category_scores_gemma":[0.0002126583,0.0001993819,0.0002853816,0.0006331013,0.0003753421,0.001040752,0.000278724,0.0009334036,0.009527551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005468675,"about_ca_system_score_gemma":0.0004046517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008227889,"about_ca_topic_score_gemma":0.001140725,"domain_scores_codex":[0.9998796,0.00001422657,0.000007036355,0.00002846505,0.00006049337,0.00001005643],"domain_scores_gemma":[0.9999372,0.00001760848,0.000007561807,0.00000754919,0.00002245621,0.000007787869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001013206,0.0001088013,0.0003828591,0.001486042,0.00001367787,0.000390861,0.0001076152,0.0008213925,0.06406077,0.07346902,0.1322635,0.7267942],"study_design_scores_gemma":[0.0000117732,0.00009008874,0.002588207,0.0001503837,0.000009111977,0.0008986114,0.00004894729,0.0003231193,0.02190026,0.01584282,0.9581205,0.00001622475],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.01561357,0.4620721,0.06905554,0.02133658,0.009220775,0.0003479537,0.0034663,0.001359392,0.4175278],"genre_scores_gemma":[0.04104149,0.3273106,0.02291221,0.002484285,0.005746691,0.0001613661,0.002583398,0.0001897804,0.5975702],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.02502717,"threshold_uncertainty_score":0.0837242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0694987296364962,"score_gpt":0.4215202967891186,"score_spread":0.3520215671526223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}