{"id":"W1579038590","doi":"10.1002/jlcr.3231","title":"Efficient, scalable and economical preparation of tris(deuterium)‐ and <sup>13</sup>C‐labelled <i>N</i>‐methyl‐<i>N</i>‐nitroso‐<i>p</i>‐toluenesulfonamide (Diazald®) and their conversion to labelled diazomethane","year":2014,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Canada Foundation for Innovation; Carleton University","keywords":"Diazomethane; Chemistry; Methanol; Cyclopropanation; Formic acid; Nitroso; Organic chemistry; Nitroso Compounds; Medicinal chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00239806,0.0004820864,0.001324378,0.0003507675,0.0003758272,0.000105703,0.0002415078,0.0004008447,0.0001049628],"category_scores_gemma":[0.0003555939,0.000382446,0.0001574566,0.0003261361,0.0006865447,0.0001980473,0.0002901639,0.0008930764,0.000006569919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000700263,"about_ca_system_score_gemma":0.00008197633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001773603,"about_ca_topic_score_gemma":0.000001803347,"domain_scores_codex":[0.996712,0.0007012146,0.00124657,0.0005394754,0.0002400997,0.0005606165],"domain_scores_gemma":[0.9951704,0.002757199,0.0005489913,0.0002297466,0.0002809018,0.00101277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005912592,0.001475026,0.006038047,0.0004328336,0.0007566916,0.00001922466,0.001592561,0.00113674,0.9679261,0.0005820353,0.002041699,0.01208641],"study_design_scores_gemma":[0.04856524,0.00283291,0.0016023,0.0003050327,0.001436722,0.001182394,0.0006187793,0.2255176,0.4716425,0.001399356,0.2436319,0.001265207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886597,0.007644301,0.0002952729,0.001830774,0.0003654787,0.0005955486,0.0000621666,0.00002742969,0.0005192739],"genre_scores_gemma":[0.9895214,0.007372386,0.001136592,0.001435104,0.0002850537,0.00001507103,0.000007219317,0.00003915728,0.0001880016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4962837,"threshold_uncertainty_score":0.9998627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03696521341257237,"score_gpt":0.3628473192521233,"score_spread":0.325882105839551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}