{"id":"W1579038590","doi":"10.1002/jlcr.3231","title":"Efficient, scalable and economical preparation of tris(deuterium)‐ and <sup>13</sup>C‐labelled <i>N</i>‐methyl‐<i>N</i>‐nitroso‐<i>p</i>‐toluenesulfonamide (Diazald®) and their conversion to labelled diazomethane","year":2014,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"Canada Foundation for Innovation; Carleton University","keywords":"Diazomethane; Chemistry; Methanol; Cyclopropanation; Formic acid; Nitroso; Organic chemistry; Nitroso Compounds; Medicinal chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002387001,0.0005542287,0.0003246317,0.0002040918,0.0002139467,0.0002545527,0.0005318238,0.0003329904,0.001790635],"category_scores_gemma":[0.0003074085,0.0002642134,0.0001754537,0.0002144148,0.0002756828,0.0003191233,0.0004256958,0.0008496151,0.0014893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004425957,"about_ca_system_score_gemma":0.000675294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006367876,"about_ca_topic_score_gemma":0.001879501,"domain_scores_codex":[0.9998509,0.00001548096,0.000007781006,0.00004134663,0.00005841891,0.00002607878],"domain_scores_gemma":[0.9998991,0.0000232572,0.00002051337,0.00001318735,0.00002393789,0.00001997027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003508443,0.0000105585,0.00004512696,0.00008897784,0.000005840116,0.00004455394,0.00001585048,0.000174876,0.9943877,0.0003125145,0.0001800026,0.004698884],"study_design_scores_gemma":[0.000005918107,0.00005300908,0.0001263239,0.000002991557,0.000004986027,0.00008592267,0.000007184467,0.0002812918,0.9939215,0.00008346517,0.005421221,0.000006188645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5870898,0.01375947,0.3562779,0.000630654,0.0004083553,0.0007304379,0.003230723,0.002348013,0.0355246],"genre_scores_gemma":[0.8129613,0.008397834,0.1567427,0.0002434613,0.00006199682,0.000446085,0.002608351,0.0003423615,0.01819577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790635,"threshold_uncertainty_score":0.005990326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03696521341257237,"score_gpt":0.3628473192521233,"score_spread":0.325882105839551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}