{"id":"W1579888339","doi":"10.4049/jimmunol.165.3.1463","title":"<i>Chlamydia trachomatis</i> Infection of Epithelial Cells Induces the Activation of Caspase-1 and Release of Mature IL-18","year":2000,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Secretion; Chlamydiae; Biology; Chlamydia trachomatis; Caspase 1; Cell culture; Microbiology; Cell biology; Immunology; Inflammation; Inflammasome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001141303,0.0003959296,0.0002214764,0.0002255675,0.0001854025,0.0004732136,0.0001203939,0.0002461873,0.002926892],"category_scores_gemma":[0.0001734847,0.0001449111,0.0004336805,0.0002017726,0.0001910642,0.000166818,0.0002041934,0.0005365445,0.0009684524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000532894,"about_ca_system_score_gemma":0.0002579771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00137346,"about_ca_topic_score_gemma":0.001546521,"domain_scores_codex":[0.9997641,0.00002816908,0.00002342117,0.00003585857,0.00005134049,0.00009698763],"domain_scores_gemma":[0.9998081,0.00003620367,0.00005499964,0.00003456456,0.00003327438,0.00003294373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001405223,0.00002875741,0.0002639541,0.00006879406,0.000003766454,0.00005700569,0.0000119412,0.00001532724,0.9982148,0.00004522778,0.0001457169,0.001004118],"study_design_scores_gemma":[0.0000178111,0.0002830535,0.01459163,0.00002015066,0.00001066098,0.000470222,0.00004807924,0.0003282923,0.9795464,0.00004142876,0.004636471,0.000005786307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845538,0.004214214,0.002469076,0.0003581588,0.0001371689,0.00006134227,0.002640039,0.0003725946,0.005193558],"genre_scores_gemma":[0.9880272,0.002173371,0.002304113,0.0002359329,0.00003858859,0.00006488091,0.00342294,0.00004464715,0.003688269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002926892,"threshold_uncertainty_score":0.009791434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399992427095039,"score_gpt":0.2593812599972776,"score_spread":0.2453813357263272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}