{"id":"W1579888339","doi":"10.4049/jimmunol.165.3.1463","title":"<i>Chlamydia trachomatis</i> Infection of Epithelial Cells Induces the Activation of Caspase-1 and Release of Mature IL-18","year":2000,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Secretion; Chlamydiae; Biology; Chlamydia trachomatis; Caspase 1; Cell culture; Microbiology; Cell biology; Immunology; Inflammation; Inflammasome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001218103,0.0001253424,0.0003829318,0.0002178208,0.0001297394,0.000004184196,0.000258058,0.0002472287,0.0005516258],"category_scores_gemma":[0.0002920366,0.00007160345,0.0001067541,0.0002886158,0.001003104,0.0001827498,0.0000414831,0.0008497211,0.00001301942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002838702,"about_ca_system_score_gemma":0.0001101719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006793356,"about_ca_topic_score_gemma":0.00001182683,"domain_scores_codex":[0.9979203,0.00107088,0.0006558622,0.0001008218,0.00007849661,0.0001736427],"domain_scores_gemma":[0.9976509,0.0007608396,0.0008309879,0.0003482502,0.0003988321,0.00001023711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00133081,0.0002492324,0.0006614846,0.00002805991,0.0004576669,7.557553e-7,0.001211346,0.0001532301,0.9717378,0.0001129367,0.000309406,0.02374727],"study_design_scores_gemma":[0.0008005946,0.000616963,0.1222919,0.00004726659,0.00009793808,0.0005937034,0.0002885505,0.000001058285,0.8737088,0.0003691841,0.001132031,0.00005209327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963319,0.002271526,0.0000595532,0.0004085413,0.0003107438,0.0002136691,0.00002477052,0.000005161278,0.0003741707],"genre_scores_gemma":[0.996217,0.003419945,0.0000245758,0.00001597131,0.00004584902,0.000002735012,0.000002821805,0.00001070019,0.0002603717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1216304,"threshold_uncertainty_score":0.6039916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399992427095039,"score_gpt":0.2593812599972776,"score_spread":0.2453813357263272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}