{"id":"W1580630655","doi":"10.1113/jphysiol.2004.063321","title":"Glycine transporter type 1 blockade changes NMDA receptor‐mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels","year":2004,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":171,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Pfizer","keywords":"NMDA receptor; Long-term potentiation; Glycine; Chemistry; 2-Amino-5-phosphonovalerate; Hippocampal formation; AMPA receptor; Glutamate receptor; Biophysics; Neuroscience; Pharmacology; Biochemistry; Receptor; Biology; Amino acid; Excitatory Amino Acid Antagonists","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006717775,0.0001999325,0.0003675627,0.0002281802,0.0001507841,0.00001636359,0.0005310342,0.00008891722,0.0001204517],"category_scores_gemma":[0.0002552544,0.0001341205,0.00004308927,0.0004852009,0.0006949956,0.0001616877,0.00008086117,0.0007453636,0.00002120451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003880351,"about_ca_system_score_gemma":0.0001144172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001732523,"about_ca_topic_score_gemma":0.000009583185,"domain_scores_codex":[0.9978148,0.0006790141,0.0003914066,0.0003009962,0.0002906333,0.0005231927],"domain_scores_gemma":[0.9986405,0.0007322409,0.0002322792,0.0001839837,0.0000582549,0.0001526911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002078441,0.0001307761,0.00007697973,0.00001530488,0.000005063156,0.0001113283,0.0004848478,0.0002046666,0.9965867,0.000004536801,0.0001534679,0.0001479315],"study_design_scores_gemma":[0.001742317,0.001492146,0.002759367,0.00002470737,0.00001049531,0.0001776069,0.00005751123,0.00004533332,0.9922059,0.0001338002,0.001226686,0.0001241884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954518,0.0003547496,0.00001015216,0.003378997,0.0005762418,0.0001864335,0.00002274526,0.0000136121,0.000005284959],"genre_scores_gemma":[0.9963978,0.002075891,0.00001283218,0.001110122,0.0001722879,0.000002670105,4.883747e-7,0.00002225716,0.0002056851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004380815,"threshold_uncertainty_score":0.5469276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05189411413466505,"score_gpt":0.3131834964144031,"score_spread":0.261289382279738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}