{"id":"W1580908187","doi":"10.1007/978-1-60761-962-8_4","title":"Functional Assays for Human Embryonic Stem Cell Pluripotency","year":2010,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Embryoid body; Embryonic stem cell; Cell biology; Induced pluripotent stem cell; Ectoderm; Biology; Endoderm; KOSR; Mesoderm; Germ layer; Stem cell; Alkaline phosphatase; Cellular differentiation; Embryo; Embryogenesis; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002694623,0.00200292,0.0005632871,0.001676932,0.0005481173,0.0008322095,0.001096783,0.00115915,0.01118859],"category_scores_gemma":[0.00172401,0.0003691004,0.001081377,0.001110129,0.0006254453,0.0006848051,0.0006374041,0.001548962,0.005378875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003409022,"about_ca_system_score_gemma":0.0004486972,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002918702,"about_ca_topic_score_gemma":0.0004352149,"domain_scores_codex":[0.9973018,0.0008635998,0.0004544097,0.000352489,0.0008421247,0.0001856075],"domain_scores_gemma":[0.9978263,0.0009520129,0.0001458723,0.0003073913,0.0006248021,0.000143585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009012991,0.00008433647,0.0003530358,0.0003223167,0.00002119381,0.00005226687,0.00009224546,0.00007558899,0.9901443,0.001171401,0.0005228751,0.007070338],"study_design_scores_gemma":[0.0000365152,0.0005205453,0.003692078,0.00008034665,0.00007257269,0.000558176,0.00006710385,0.0008228698,0.9733675,0.0008708893,0.0198837,0.00002779785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2868006,0.01681421,0.6091368,0.000936227,0.001020118,0.002664961,0.01717909,0.002509887,0.06293809],"genre_scores_gemma":[0.5489147,0.01273193,0.3323281,0.001240542,0.000348449,0.004666016,0.04328534,0.0007658745,0.05571913],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01118859,"threshold_uncertainty_score":0.03742957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0284595471200011,"score_gpt":0.3746467700825932,"score_spread":0.3461872229625921,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}