{"id":"W1580941828","doi":"","title":"NOVEL SMALL MOLECULE INHIBITORS OF TNF- AND RANKL-SIGNALING PREVENT COLLAGEN INDUCED ARTHRITIS","year":2009,"lang":"en","type":"article","venue":"","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre","funders":"","keywords":"Medicine; RANKL; Arthritis; Tumor necrosis factor alpha; Signal transduction; Inflammatory arthritis; Small molecule; Cancer research; Cell biology; Immunology; Internal medicine; Receptor; Biochemistry; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158594,0.0004292128,0.000598239,0.0002789675,0.0002178136,0.0003922072,0.0003687086,0.0003121831,0.002932928],"category_scores_gemma":[0.0001364046,0.0002168813,0.0002648063,0.0001422948,0.0002489969,0.0002522363,0.0001516081,0.001314404,0.0007807937],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631339,"about_ca_system_score_gemma":0.000371505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003911466,"about_ca_topic_score_gemma":0.001924809,"domain_scores_codex":[0.9999164,0.000009151028,0.000005687528,0.000007087557,0.00002558542,0.00003601144],"domain_scores_gemma":[0.9999413,0.000009925386,0.00001557366,0.000003835909,0.000005737851,0.00002350669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006504764,0.001812122,0.0004871369,0.0005205737,0.0001211185,0.0003372455,0.00006245606,0.000722337,0.8966184,0.001432719,0.002780271,0.08860084],"study_design_scores_gemma":[0.0130954,0.02809807,0.01401555,0.000101835,0.0004446592,0.002500326,0.0001667095,0.005001534,0.8860297,0.001357891,0.04910369,0.00008464508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9593483,0.02576987,0.005726033,0.0007845515,0.0005944632,0.0002395505,0.00053633,0.0004853515,0.006515534],"genre_scores_gemma":[0.9715253,0.01365085,0.00476246,0.0002991387,0.0001542572,0.0001717257,0.0007392747,0.00002887879,0.008668019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002932928,"threshold_uncertainty_score":0.00981164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02064922908026619,"score_gpt":0.2632185858122615,"score_spread":0.2425693567319953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}