{"id":"W1581059395","doi":"10.6000/1929-2279.2015.04.02.1","title":"Bufalin Induces Apoptosis of MDA-MB-231 Cell Through Activation of JNK/p53 Pathway","year":2015,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Bufalin; Apoptosis; MAPK/ERK pathway; Chemistry; Cancer research; Cancer; Breast cancer; Pharmacology; Internal medicine; Kinase; Biology; Medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006066807,0.0003516717,0.0002469758,0.0003170384,0.0002406679,0.0001773926,0.0001455498,0.0002146183,0.001799834],"category_scores_gemma":[0.0001028713,0.00008822657,0.0002566293,0.0002350072,0.0001305476,0.0002351661,0.000138904,0.0004418546,0.0002549858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002726743,"about_ca_system_score_gemma":0.0002204258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001224164,"about_ca_topic_score_gemma":0.00188912,"domain_scores_codex":[0.999904,0.00001356899,0.000007645322,0.00001127883,0.00003012242,0.0000333044],"domain_scores_gemma":[0.999971,0.000004836113,0.000007944755,0.000002346047,0.000007319736,0.000006492067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004469567,0.0001114214,0.0005255771,0.0001439103,0.00001140003,0.0001951309,0.00003260514,0.00006606385,0.992584,0.0001133194,0.000226532,0.005543212],"study_design_scores_gemma":[0.00002974216,0.0005039294,0.006252113,0.00001045345,0.00001937165,0.0003959295,0.00006624805,0.0005845177,0.988363,0.0000781731,0.003691624,0.000004981813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860763,0.006802741,0.002044126,0.0004297868,0.00009985649,0.00005114641,0.000490609,0.0001236503,0.00388185],"genre_scores_gemma":[0.9933445,0.003041471,0.0008614821,0.0001049914,0.00001605813,0.00005118895,0.0004482459,0.000006099153,0.002125892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001799834,"threshold_uncertainty_score":0.006021023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4402836992531155,"score_gpt":0.5547447525320045,"score_spread":0.114461053278889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}