{"id":"W1581533309","doi":"10.1038/79767","title":"Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1","year":2000,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Cell biology; Exocytosis; Chemotaxis; Chemokine; Granule (geology); Chemistry; Tyrosine kinase; Signal transduction; Biology; Receptor; Secretion; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006835146,0.0001008207,0.0001181584,0.00002064477,0.00005496349,0.000006341732,0.00007244083,0.0004398765,0.0002662155],"category_scores_gemma":[0.00005481095,0.00009505588,0.00003291666,0.00006938576,0.00006896409,0.000007373889,0.00002115535,0.0001705395,0.000002723118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006853902,"about_ca_system_score_gemma":0.00001686096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003607559,"about_ca_topic_score_gemma":0.000002361178,"domain_scores_codex":[0.9993943,0.00005150526,0.0001496609,0.000216912,0.0000623915,0.0001252356],"domain_scores_gemma":[0.9996615,0.00001188919,0.00007330982,0.0001802794,0.00005556262,0.00001746947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002190525,0.00003275781,0.00005327387,0.000007011088,0.00002186971,3.014529e-7,0.00002860754,0.00001712319,0.9831651,0.0004947623,0.001422126,0.01453803],"study_design_scores_gemma":[0.0005144288,0.00021201,0.001465381,0.00001511589,0.000008844031,0.000007799852,0.00001573662,0.00003063363,0.958671,0.0007452574,0.03821846,0.00009536564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917958,0.006208055,0.001063823,0.0002256257,0.00009797252,0.0001018609,0.00001318693,0.00001008469,0.0004835894],"genre_scores_gemma":[0.9971553,0.0006557463,0.001013074,0.0001763411,0.00006642736,0.000005867518,0.0002848507,0.00001283616,0.0006295563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03679634,"threshold_uncertainty_score":0.3876266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003229645076029552,"score_gpt":0.2186796656861016,"score_spread":0.215450020610072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}