{"id":"W1581852456","doi":"10.1002/9781118185537.ch12","title":"Targeting Epigenetic Abnormalities in the Brain","year":2012,"lang":"en","type":"other","venue":"","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Epigenetics; Neuroscience; Computational biology; Biology; Medicine; Bioinformatics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002174876,0.0005416276,0.0004020456,0.0005708497,0.0002564968,0.0006551501,0.0003896193,0.0004223347,0.00828548],"category_scores_gemma":[0.000125082,0.0001210149,0.0002640754,0.0003291113,0.0003116514,0.0003148531,0.0004177426,0.0007670745,0.001114248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005125495,"about_ca_system_score_gemma":0.0003870215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006295005,"about_ca_topic_score_gemma":0.00267948,"domain_scores_codex":[0.9999382,0.000007312609,0.000002809832,0.00001307104,0.00002481262,0.00001375193],"domain_scores_gemma":[0.9999584,0.000006614992,0.0000080848,0.00000662251,0.000006469013,0.0000138724],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009223168,0.0002993191,0.001418799,0.0008913947,0.0001411419,0.00168071,0.00007296151,0.002404222,0.6158525,0.03706379,0.01748504,0.3217678],"study_design_scores_gemma":[0.0001665377,0.0004130119,0.004501092,0.0001317006,0.0002452194,0.003775067,0.00007878893,0.00231466,0.545304,0.007568727,0.4354651,0.0000361761],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.4422308,0.1755958,0.08254278,0.009188117,0.00170777,0.0003390042,0.004705564,0.00369242,0.2799978],"genre_scores_gemma":[0.7504609,0.08548521,0.02312231,0.001328418,0.0002624163,0.0001772132,0.001996215,0.0003286461,0.1368387],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.00828548,"threshold_uncertainty_score":0.02771771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00871243876816711,"score_gpt":0.2273150126065849,"score_spread":0.2186025738384178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}