{"id":"W1583134507","doi":"10.1155/2007/862917","title":"Delayed-Release Oral Mesalamine 4.8 g/day (800 mg tablets) Compared with 2.4 g/day (400 mg tablets) for the Treatment of Mildly to Moderately Active Ulcerative Colitis: The ASCEND I Trial","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval","funders":"Procter and Gamble","keywords":"Medicine; Ulcerative colitis; Adverse effect; Internal medicine; Gastroenterology; Clinical endpoint; Randomized controlled trial; Subgroup analysis; Clinical trial; Oral administration; Intention-to-treat analysis; Confidence interval; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007019705,0.0003098155,0.0004679205,0.0001483909,0.0002766615,0.00004198289,0.0004122711,0.0001226743,0.00005228144],"category_scores_gemma":[0.0001088744,0.0001937341,0.0002327651,0.00009146227,0.0003541435,0.00001621391,0.00001956467,0.0001585047,0.000002049779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228327,"about_ca_system_score_gemma":0.001040817,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001146084,"about_ca_topic_score_gemma":0.2113227,"domain_scores_codex":[0.9978043,0.000360223,0.000591807,0.0002867467,0.0001713736,0.0007855555],"domain_scores_gemma":[0.9978092,0.0001154804,0.0004315646,0.0003772586,0.0005742084,0.0006922286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9199854,0.0009330529,0.01457948,0.00003696818,0.005285954,0.001635084,0.004106194,0.01602973,0.01116549,0.000264423,0.02160195,0.004376237],"study_design_scores_gemma":[0.1977779,0.09643228,0.5291966,0.0001636783,0.002572038,0.001458498,0.005568143,0.002366849,0.0259409,0.0001514693,0.1372105,0.001161083],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880735,0.0001311971,0.008310753,0.001120998,0.0004411055,0.001256442,0.0005839119,0.000002732663,0.00007930632],"genre_scores_gemma":[0.9975098,0.00002812438,0.0003792544,0.0011793,0.0005266885,0.00007925023,0.00006702249,0.00003933498,0.0001912157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7222075,"threshold_uncertainty_score":0.8030686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249435581749355,"score_gpt":0.2479026317344526,"score_spread":0.235408275916959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}