{"id":"W1583134507","doi":"10.1155/2007/862917","title":"Delayed-Release Oral Mesalamine 4.8 g/day (800 mg tablets) Compared with 2.4 g/day (400 mg tablets) for the Treatment of Mildly to Moderately Active Ulcerative Colitis: The ASCEND I Trial","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval","funders":"Procter and Gamble","keywords":"Medicine; Ulcerative colitis; Adverse effect; Internal medicine; Gastroenterology; Clinical endpoint; Randomized controlled trial; Subgroup analysis; Clinical trial; Oral administration; Intention-to-treat analysis; Confidence interval; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001475338,0.001070589,0.00214433,0.0003176323,0.0003017678,0.0006398717,0.0008244731,0.001121241,0.003235732],"category_scores_gemma":[0.001448801,0.0003640949,0.001536331,0.0002425259,0.0006130846,0.0005029658,0.0002922088,0.002268877,0.0004311853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003935765,"about_ca_system_score_gemma":0.0006330071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005957527,"about_ca_topic_score_gemma":0.001123062,"domain_scores_codex":[0.9996141,0.0002325028,0.00002475237,0.00005242257,0.00003697669,0.00003925116],"domain_scores_gemma":[0.9990715,0.0002813298,0.0002714825,0.00005451603,0.00005212305,0.0002689989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9766718,0.003524743,0.0006375718,0.0006416332,0.0006447677,0.00003398977,0.00003477691,0.0001856946,0.002827334,0.00006285332,0.0006738073,0.01406099],"study_design_scores_gemma":[0.9104379,0.08369292,0.003413552,0.00005883875,0.0006934133,0.00004680613,0.00001702339,0.0004171262,0.0005927795,0.00006127208,0.0005553314,0.0000130549],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890526,0.006897212,0.0002852016,0.0004312199,0.000369559,0.001115418,0.0004770719,0.00006221513,0.001309515],"genre_scores_gemma":[0.989475,0.003334783,0.001135279,0.0008943342,0.000573894,0.001539061,0.0008132742,0.00001409433,0.002220236],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003235732,"threshold_uncertainty_score":0.01082456,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01249435581749355,"score_gpt":0.2479026317344526,"score_spread":0.235408275916959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}