{"id":"W1583413364","doi":"10.1016/j.jacc.2013.06.044","title":"Secretory Phospholipase A2-IIA and Cardiovascular Disease","year":2013,"lang":"en","type":"review","venue":"Journal of the American College of Cardiology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Economic and Social Research Council; Servier; Medical Research Council; National Institutes of Health; Sanofi; Top Institute Pharma; Stockholms Läns Landsting; Agence Nationale de la Recherche; Hjärt-Lungfonden; Abbott Laboratories; Astellas Pharma; Vetenskapsrådet; Eisai; Gentofte Hospital; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Daiichi-Sankyo; British Heart Foundation; Bundesministerium für Bildung und Forschung; Rigshospitalet; Erasmus Universiteit Rotterdam; Daiichi Sankyo Europe; Karolinska Institutet; ZonMw; Heart and Stroke Foundation of Canada; Torsten Söderbergs Stiftelse; Research Promotion Foundation; Knut och Alice Wallenbergs Stiftelse; University of Bristol; Diabetes UK; Ministero della Salute; Anthera; National Institute for Health and Care Research; Wellcome Trust; Intarcia Therapeutics; Cancer Research UK; Erasmus Medisch Centrum; Health and Safety Executive; Boston Scientific Corporation; University of California, San Diego; Sundhed og Sygdom, Det Frie Forskningsråd; Brigham and Women's Hospital; Pfizer; GlaxoSmithKline; European Commission; AstraZeneca; Bristol-Myers Squibb; John D. and Catherine T. MacArthur Foundation; Eli Lilly and Company; Amgen","keywords":"Medicine; Disease; Phospholipase A2; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005071173,0.0008885586,0.001108864,0.0008137589,0.0001923714,0.001157624,0.0005219394,0.001013733,0.001584285],"category_scores_gemma":[0.004937842,0.0003591284,0.003529461,0.00130202,0.0004174053,0.0003085992,0.0004178545,0.0008878346,0.0001374132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000375585,"about_ca_system_score_gemma":0.0009760323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001490645,"about_ca_topic_score_gemma":0.001032645,"domain_scores_codex":[0.9974856,0.00147714,0.0002198491,0.0005051068,0.0002193739,0.00009285022],"domain_scores_gemma":[0.9970703,0.00171786,0.0007177734,0.0001825635,0.00018489,0.0001264907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01144124,0.0002097337,0.8330707,0.007315523,0.1048847,0.0006390542,0.0001218794,0.002106775,0.005776058,0.0009909798,0.0006912394,0.03275207],"study_design_scores_gemma":[0.002726668,0.003847145,0.8839464,0.002037175,0.0878181,0.002341874,0.0002147712,0.003700165,0.003660522,0.002733109,0.006912285,0.00006191123],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6582385,0.3304763,0.005424646,0.001819512,0.0004173558,0.0001802037,0.001167268,0.00005690964,0.002219312],"genre_scores_gemma":[0.9784045,0.01895976,0.001278282,0.0003963252,0.0002253597,0.00006266268,0.0003112157,0.000005525688,0.0003564113],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.005071173,"threshold_uncertainty_score":0.02681929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01766531927037081,"score_gpt":0.265180314997538,"score_spread":0.2475149957271672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}