{"id":"W1583529973","doi":"10.1182/blood-2010-07-298851","title":"Regulation of S100A10 by the PML-RAR-α oncoprotein","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University","keywords":"Plasmin; Acute promyelocytic leukemia; Retinoic acid; Fibrinolysis; Leukemia; Cancer research; Promyelocytic leukemia protein; Tretinoin; Retinoic acid receptor; Biology; Immunology; Medicine; Cell culture; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009320021,0.0003983902,0.0002054928,0.0002851983,0.0001113514,0.000369593,0.0001439849,0.0002420539,0.0008505584],"category_scores_gemma":[0.0001355832,0.0001340548,0.0002241563,0.0001343804,0.000427737,0.0001647723,0.0001847432,0.0004454666,0.000564545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004266693,"about_ca_system_score_gemma":0.0001738031,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006353093,"about_ca_topic_score_gemma":0.000792819,"domain_scores_codex":[0.9998524,0.00003629522,0.00001495574,0.00002829966,0.00003479968,0.00003330263],"domain_scores_gemma":[0.9998842,0.00001847988,0.00004870513,0.00001827355,0.00001085782,0.00001943491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008065349,0.00000995244,0.0001485298,0.00001139156,0.000002688188,0.00007090295,0.000007303073,0.00002600389,0.99878,0.00007224019,0.0000163761,0.0007740115],"study_design_scores_gemma":[0.00001826833,0.0001421008,0.006136298,0.00000495929,0.00001084581,0.0004458518,0.00003768196,0.0005330609,0.9896153,0.0000646281,0.00298712,0.000003822829],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919598,0.003332165,0.002465867,0.0001447337,0.00003575624,0.00001912952,0.000257916,0.0001185936,0.001666132],"genre_scores_gemma":[0.9940318,0.001305188,0.001370776,0.00004025907,0.000006273343,0.00002577637,0.00030659,0.00001683162,0.002896474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008505584,"threshold_uncertainty_score":0.003095686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009394667529218083,"score_gpt":0.2016841537336891,"score_spread":0.192289486204471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}