{"id":"W1585124267","doi":"10.4049/jimmunol.0903177","title":"The p110δ Isoform of Phosphatidylinositol 3-Kinase Controls the Quality of Secondary Anti- <i>Leishmania</i> Immunity by Regulating Expansion and Effector Function of Memory T Cell Subsets","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Queen Mary University of London; Manitoba Health Research Council","keywords":"Effector; Biology; Leishmania major; Adoptive cell transfer; Immunology; Immune system; T cell; Cell biology; Leishmania; Cutaneous leishmaniasis; Cancer research; Leishmaniasis; Parasite hosting","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001298564,0.0004023446,0.0002128804,0.0002180016,0.0001078487,0.0004822741,0.0003030309,0.0003068492,0.0006166785],"category_scores_gemma":[0.0001185209,0.000192798,0.0001586448,0.0001248325,0.0004059962,0.0002444143,0.0002430446,0.0006238465,0.0003073994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002609583,"about_ca_system_score_gemma":0.0001388074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002138131,"about_ca_topic_score_gemma":0.000258614,"domain_scores_codex":[0.9998703,0.0000147514,0.00001539362,0.00003959497,0.00002161831,0.00003838039],"domain_scores_gemma":[0.9997241,0.0000181301,0.0001458143,0.00002815584,0.00001549364,0.00006819306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002128976,0.00002144178,0.0004396109,0.00001858539,0.000003071122,0.00004153157,0.000007681352,0.00003791507,0.9981159,0.00005064899,0.00001672772,0.00103405],"study_design_scores_gemma":[0.00005611983,0.0006298047,0.0126394,0.000007594037,0.00003068416,0.0006240534,0.00004129053,0.000997995,0.9834847,0.0001255978,0.001354166,0.000008566532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968934,0.0006126701,0.001630204,0.00005394787,0.00001185383,0.00001332548,0.000119811,0.00008831277,0.0005764227],"genre_scores_gemma":[0.9976527,0.0004590178,0.0008469592,0.00003271459,0.00000907536,0.00001123645,0.0001621462,0.00002005257,0.0008061427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006166785,"threshold_uncertainty_score":0.002062976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01291946333342177,"score_gpt":0.2808859505231364,"score_spread":0.2679664871897146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}