{"id":"W1585166895","doi":"10.1111/j.1365-2133.2011.10489.x","title":"CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes","year":2011,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; Vancouver General Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Indoleamine 2,3-dioxygenase; Downregulation and upregulation; Basal cell carcinoma; Kynurenine; Biology; Keratinocyte; Cancer research; CXCR3; Carcinogenesis; Western blot; Molecular biology; Immunology; Immune system; In vitro; Biochemistry; Medicine; Pathology; Chemokine; Gene; Basal cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152727,0.0001697181,0.0001630421,0.000136823,0.0001375078,0.0003082349,0.00005812912,0.0001750328,0.00307888],"category_scores_gemma":[0.00008748665,0.00008235379,0.0002655387,0.00007587227,0.0001170434,0.0001217378,0.0001507128,0.0004072321,0.0007466335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000248451,"about_ca_system_score_gemma":0.0002036684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007702293,"about_ca_topic_score_gemma":0.001127819,"domain_scores_codex":[0.9998462,0.0000297333,0.00001109154,0.00001902129,0.00003617426,0.0000577933],"domain_scores_gemma":[0.999923,0.00001239007,0.00001795509,0.000007703021,0.00001595742,0.00002290884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001897101,0.00004736726,0.001087532,0.0001042393,0.000005305001,0.00007798824,0.00002970705,0.00004479688,0.9960839,0.00005860663,0.0001782226,0.002092585],"study_design_scores_gemma":[0.0000630301,0.001024402,0.05638435,0.0000546074,0.00004229341,0.0008771113,0.0003170176,0.001236613,0.9309786,0.00007800567,0.008931327,0.00001269521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920142,0.00309959,0.001112414,0.000139505,0.00003885086,0.00005209282,0.0005054306,0.00007094529,0.002966825],"genre_scores_gemma":[0.9950897,0.0007707457,0.0009230335,0.00009150615,0.00001244326,0.00004154548,0.0004178859,0.000008690751,0.002644493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00307888,"threshold_uncertainty_score":0.01029986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02788231292972241,"score_gpt":0.2188410864020706,"score_spread":0.1909587734723482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}