{"id":"W1585736644","doi":"10.1002/pro.761","title":"Roles of the N‐ and C‐terminal sequences in Hsp27 self‐association and chaperone activity","year":2011,"lang":"en","type":"article","venue":"Protein Science","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Michael Smith Health Research BC","keywords":"Hsp27; Chaperone (clinical); Oligomer; Protein subunit; Heat shock protein; Biology; Biophysics; Biochemistry; Hsp70; Cell biology; Chemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638444,0.0002411765,0.0002280029,0.0001217399,0.0001810742,0.0002356904,0.0002502719,0.0002025122,0.0006768674],"category_scores_gemma":[0.0002721953,0.000137798,0.0002863074,0.000139929,0.0002855563,0.0002752085,0.000196006,0.0004037688,0.0002726527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003163585,"about_ca_system_score_gemma":0.0003827722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009057692,"about_ca_topic_score_gemma":0.0008827376,"domain_scores_codex":[0.9998744,0.0000229838,0.0000157551,0.00002310956,0.00003820073,0.00002561535],"domain_scores_gemma":[0.9996978,0.00005714507,0.00008739081,0.00003791675,0.00004671474,0.00007312228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001326253,0.00001738319,0.0006203564,0.00002530387,0.000005040526,0.00006318899,0.00001781763,0.000235354,0.9980848,0.00005954347,0.000009233198,0.0007294762],"study_design_scores_gemma":[0.00001562809,0.0002082814,0.02738024,0.0000132388,0.00002311509,0.0008299882,0.00009367184,0.001459099,0.9687454,0.0001184792,0.001096436,0.00001652914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983538,0.0005846965,0.0007062859,0.0000199809,0.000002966354,0.000004341127,0.0000740648,0.000008996947,0.0002447659],"genre_scores_gemma":[0.9983552,0.000219603,0.0007510985,0.00002165914,0.000001505843,0.000008316829,0.0002470962,0.000008273082,0.000387201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009057692,"threshold_uncertainty_score":0.002295315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02090500722334597,"score_gpt":0.2813875510699529,"score_spread":0.260482543846607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}