{"id":"W1585736644","doi":"10.1002/pro.761","title":"Roles of the N‐ and C‐terminal sequences in Hsp27 self‐association and chaperone activity","year":2011,"lang":"en","type":"article","venue":"Protein Science","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Michael Smith Health Research BC","keywords":"Hsp27; Chaperone (clinical); Oligomer; Protein subunit; Heat shock protein; Biology; Biophysics; Biochemistry; Hsp70; Cell biology; Chemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009541883,0.00004909896,0.00005877099,0.00003676753,0.00008898124,0.0000158756,0.0002016042,0.00004820877,0.000003194941],"category_scores_gemma":[0.0003136453,0.00003481309,0.000009278097,0.0001799038,0.000347224,0.00001504836,0.0002502432,0.00006772852,3.847876e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002424093,"about_ca_system_score_gemma":0.0001483402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001784531,"about_ca_topic_score_gemma":0.0001850012,"domain_scores_codex":[0.9992461,0.00006755151,0.00007401282,0.0002097249,0.0002290822,0.0001734957],"domain_scores_gemma":[0.9997045,0.000005829896,0.00004868199,0.0001440471,0.00005696708,0.00003992762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001150291,0.00002170433,0.04451765,0.00001336063,0.000001379174,3.697963e-7,0.0003018236,1.410756e-7,0.9502503,0.00005158471,5.097187e-7,0.004829629],"study_design_scores_gemma":[0.00008902503,0.00009622532,0.1501564,0.00001441732,8.457439e-7,0.000003283931,0.00003512997,0.000104257,0.8492771,0.0001337096,0.00004993628,0.00003970371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998939,0.0001481169,0.00002498021,0.0001222228,0.00001121112,0.0003088869,0.000001774421,0.00000219609,0.0004415573],"genre_scores_gemma":[0.9991196,0.00002824717,0.0007085195,0.000009421953,0.000009616961,0.00003245637,8.531882e-8,0.000002197404,0.00008987661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1056387,"threshold_uncertainty_score":0.1419636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02090500722334597,"score_gpt":0.2813875510699529,"score_spread":0.260482543846607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}